Introduction：Basic information about CAS 5974-93-6|2',3'-Didehydro-2',3'-dideoxyuridine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 2',3'-Didehydro-2',3'-dideoxyuridine |
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| CAS Number | 5974-93-6 | Molecular Weight | 210.19 |
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| Density | 1.448g/cm3 | Boiling Point | 443.4ºC at 760 mmHg |
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| Molecular Formula | C9H10N2O4 | Melting Point | / |
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| MSDS | / | Flash Point | 221.9ºC |
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Names
| Name | 1-[(2R,5S)-5-(hydroxymethyl)-2,5-dihydrofuran-2-yl]pyrimidine-2,4-dione |
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| Synonym | More Synonyms |
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2',3'-Didehydro-2',3'-dideoxyuridine BiologicalActivity
| Description | 2',3'-Didehydro-2',3'-dideoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>Cell Cycle/DNA Damage >>Nucleoside Antimetabolite/Analog |
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| References | [1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. |
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Chemical & Physical Properties
| Density | 1.448g/cm3 |
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| Boiling Point | 443.4ºC at 760 mmHg |
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| Molecular Formula | C9H10N2O4 |
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| Molecular Weight | 210.19 |
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| Flash Point | 221.9ºC |
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| Exact Mass | 210.06400 |
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| PSA | 84.32000 |
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| Index of Refraction | 1.592 |
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| InChIKey | NZXWQUCGACTHLK-POYBYMJQSA-N |
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| SMILES | O=c1ccn(C2C=CC(CO)O2)c(=O)[nH]1 |
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Synonyms
| ddeUrd |
| D4U |
| 2',3'-Dideoxyuridinene |
| 2',3'-Didehydro-2',3'-dideoxyuridine |
