Introduction:Basic information about CAS 3868-31-3|8-hydroxyguanosine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 8-hydroxyguanosine |
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| CAS Number | 3868-31-3 | Molecular Weight | 299.240 |
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| Density | 2.4±0.1 g/cm3 | Boiling Point | / |
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| Molecular Formula | C10H13N5O6 | Melting Point | 232-235ºC |
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| MSDS | / | Flash Point | / |
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Names
| Name | 8-hydroxyguanosine |
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| Synonym | More Synonyms |
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8-hydroxyguanosine BiologicalActivity
| Description | 8-Hydroxyguanosine is a systematic marker of oxidative stress and a marker of hydroxyl radical damage to RNA. |
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| Related Catalog | Research Areas >>Metabolic DiseaseResearch Areas >>Neurological DiseaseNatural Products >>Others |
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| Target | Human Endogenous Metabolite |
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| References | [1]. Fiala ES, et al. Oxidative DNA and RNA damage in the livers of Sprague-Dawley rats treated with the hepatocarcinogen 2-nitropropane. Cancer Res. 1989 Oct 15;49(20):5518-22. [2]. Abe T, et al. Remarkable increase in the concentration of 8-hydroxyguanosine in cerebrospinal fluid from patients with Alzheimer's disease. J Neurosci Res. 2002 Nov 1;70(3):447-50. |
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Chemical & Physical Properties
| Density | 2.4±0.1 g/cm3 |
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| Melting Point | 232-235ºC |
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| Molecular Formula | C10H13N5O6 |
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| Molecular Weight | 299.240 |
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| Exact Mass | 299.086578 |
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| PSA | 179.74000 |
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| LogP | -0.97 |
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| Index of Refraction | 2.007 |
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| InChIKey | FPGSEBKFEJEOSA-UHFFFAOYSA-N |
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| SMILES | Nc1nc2c([nH]c(=O)n2C2OC(CO)C(O)C2O)c(=O)[nH]1 |
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| Storage condition | -20°C Freezer |
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Synonyms
| 8-Hydroxy Guanosine |
| 8-OXO-G |
| 8-OXOGUANOSINE |
| 8-Oxyguanosin |
| 7,8-dihydro-8-oxo-Guanosine |
| 7,8-Dihydroguanosine, 8-oxo- |
| 7,8-dihydro-8-oxo-guanosin |
| 8-OHG |
| 8-oxo-7,8-dihydro-guanosine |
| 8-OH-GUO |
| 8-Hydroxy-guanosin |
| 8-Oxo-7,8-dihydroguanosine |
| 8-Oxo-D-guanosine |
| 8-Oxoguanosin |