CAS 3868-31-3|8-hydroxyguanosine

Introduction:Basic information about CAS 3868-31-3|8-hydroxyguanosine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Name8-hydroxyguanosine
CAS Number3868-31-3Molecular Weight299.240
Density2.4±0.1 g/cm3Boiling Point/
Molecular FormulaC10H13N5O6Melting Point232-235ºC
MSDS/Flash Point/

Names

Name8-hydroxyguanosine
SynonymMore Synonyms

8-hydroxyguanosine BiologicalActivity

Description8-Hydroxyguanosine is a systematic marker of oxidative stress and a marker of hydroxyl radical damage to RNA.
Related CatalogResearch Areas >>Metabolic DiseaseResearch Areas >>Neurological DiseaseNatural Products >>Others
Target

Human Endogenous Metabolite

References

[1]. Fiala ES, et al. Oxidative DNA and RNA damage in the livers of Sprague-Dawley rats treated with the hepatocarcinogen 2-nitropropane. Cancer Res. 1989 Oct 15;49(20):5518-22.

[2]. Abe T, et al. Remarkable increase in the concentration of 8-hydroxyguanosine in cerebrospinal fluid from patients with Alzheimer's disease. J Neurosci Res. 2002 Nov 1;70(3):447-50.

Chemical & Physical Properties

Density2.4±0.1 g/cm3
Melting Point232-235ºC
Molecular FormulaC10H13N5O6
Molecular Weight299.240
Exact Mass299.086578
PSA179.74000
LogP-0.97
Index of Refraction2.007
InChIKeyFPGSEBKFEJEOSA-UHFFFAOYSA-N
SMILESNc1nc2c([nH]c(=O)n2C2OC(CO)C(O)C2O)c(=O)[nH]1
Storage condition-20°C Freezer

Synonyms

8-Hydroxy Guanosine
8-OXO-G
8-OXOGUANOSINE
8-Oxyguanosin
7,8-dihydro-8-oxo-Guanosine
7,8-Dihydroguanosine, 8-oxo-
7,8-dihydro-8-oxo-guanosin
8-OHG
8-oxo-7,8-dihydro-guanosine
8-OH-GUO
8-Hydroxy-guanosin
8-Oxo-7,8-dihydroguanosine
8-Oxo-D-guanosine
8-Oxoguanosin
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