CAS 67219-55-0|5'-O-Dimethoxytrityl-N-benzoyl-desoxycytidine

Introduction：Basic information about CAS 67219-55-0|5'-O-Dimethoxytrityl-N-benzoyl-desoxycytidine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Articles2
6. Synonyms

Common Name	5'-O-Dimethoxytrityl-N-benzoyl-desoxycytidine
CAS Number	67219-55-0	Molecular Weight	633.69000
Density	1.27 g/cm3	Boiling Point	/
Molecular Formula	C₃₇H₃₅N₃O₇	Melting Point	119 °C
MSDS	ChineseUSA	Flash Point	/
Symbol	GHS08	Signal Word	Danger

Names

Name	N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine
Synonym	More Synonyms

BiologicalActivity

Description	N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine (5'-O-DMT-N4-Bz-dC) can be used for synthesis oligodeoxynucleotides containing a 3'-S-phosphorothiolate (3'-PS) linkage. N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine is an useful tool for probing enzyme-catalyzed cleavage processes in DNA[1].
Related Catalog	Research Areas >>OthersSignaling Pathways >>Others >>Others
References	[1]. James W Gaynor, et al. Synthesis of the 3'-thio-nucleosides and subsequent automated synthesis of oligodeoxynucleotides containing a 3'-S-phosphorothiolate linkage. Nat Protoc. 2007;2(12):3122-35.

Chemical & Physical Properties

Density	1.27 g/cm3
Melting Point	119 °C
Molecular Formula	C₃₇H₃₅N₃O₇
Molecular Weight	633.69000
Exact Mass	633.24800
PSA	121.14000
LogP	5.24290
Index of Refraction	58 ° (C=1, MeOH)
InChIKey	MYSNCIZBPUPZMQ-VOTWKOMSSA-N
SMILES	COc1ccc(C(OCC2OC(n3ccc(NC(=O)c4ccccc4)nc3=O)CC2O)(c2ccccc2)c2ccc(OC)cc2)cc1
Storage condition	−20°C

Safety Information

Symbol	GHS08
Signal Word	Danger
Hazard Statements	H340-H350
Precautionary Statements	P201-P280-P308 + P313
Personal Protective Equipment	Eyeshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
Hazard Codes	Xn: Harmful;
Risk Phrases	R40
Safety Phrases	S36/37
RIDADR	NONH for all modes of transport
WGK Germany	1

Articles2

Diels-Alder cycloadditions in water for the straightforward preparation of peptide-oligonucleotide conjugates.

Nucleic Acids Res. 34(3) , e24, (2006)

The Diels-Alder reaction between diene-modified oligonucleotides and maleimide-derivatized peptides afforded peptide-oligonucleotide conjugates with high purity and yield. Synthesis of the reagents wa...

Aldrichimica Acta 20 , 52, (1987)

Synonyms

N-[1-[(2R,4S,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-hydroxyoxolan-2-yl]-2-oxopyrimidin-4-yl]benzamide

EINECS 266-605-9

MFCD00010114

5'-O-Dimethoxytrityl-N-benzoyl-desoxycytidine

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