Introduction：Basic information about CAS 20736-08-7|Saikosaponin C, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Saikosaponin C |
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| CAS Number | 20736-08-7 | Molecular Weight | 943.122 |
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| Density | 1.4±0.1 g/cm3 | Boiling Point | / |
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| Molecular Formula | C48H78O18 | Melting Point | 310-314ºC |
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| MSDS | ChineseUSA | Flash Point | / |
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Names
| Name | Saikosaponin C |
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| Synonym | More Synonyms |
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Saikosaponin C BiologicalActivity
| Description | Saikosaponin C is a bioactive component found in radix bupleuri, targets amyloid beta and tau in Alzheimer's disease. Saikosaponin C inhibits the secretion of both Aβ1-40 and Aβ1-42, and suppresses abnormal tau phosphorylation, but shows no effect on BACE1 activity and expression[1]. |
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| Related Catalog | Research Areas >>Neurological Disease |
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| References | [1]. Lee TH1, et al. A potential therapeutic effect of saikosaponin C as a novel dual-target anti-Alzheimer agent. J Neurochem. 2016 Mar;136(6):1232-1245. |
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Chemical & Physical Properties
| Density | 1.4±0.1 g/cm3 |
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| Melting Point | 310-314ºC |
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| Molecular Formula | C48H78O18 |
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| Molecular Weight | 943.122 |
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| Exact Mass | 942.518799 |
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| PSA | 287.14000 |
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| LogP | 2.35 |
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| Index of Refraction | 1.632 |
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Safety Information
| Hazard Codes | Xi |
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| Risk Phrases | 36/37/38 |
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| Safety Phrases | S26 |
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Synonyms
| Saikosaponin c standard |
| (3β,16β)-16,23-dihydroxy-13,28-epoxyolean-11-en-3-yl 6-deoxy-α-L-altropyranosyl-(1->4)-[β-D-glucopyranosyl-(1->6)]-β-D-glucopyranoside |
| SaikosaponinC |
| β-D-glucopyranoside, (3β,16β)-13,28-epoxy-16,23-dihydroxyolean-11-en-3-yl O-6-deoxy-α-L-altropyranosyl-(1->4)-O-[β-D-glucopyranosyl-(1->6)]- |
| Saikosaponin C |
| SAIKOSAPONIN A(P) |
| Saikosaponian C |
| β-D-Glucopyranoside, (3β,16β)-13,28-epoxy-16,23-dihydroxyolean-11-en-3-yl O-6-deoxy-β-L-altropyranosyl-(1->4)-O-[β-D-glucopyranosyl-(1->6)]- |
| chikusakoside II |
| SAIKOSAPONIN C(P) |
| (3β,16β)-16,23-Dihydroxy-13,28-epoxyolean-11-en-3-yl 6-deoxy-β-L-altropyranosyl-(1->4)-[β-D-glucopyranosyl-(1->6)]-β-D-glucopyranoside |
