CAS 5707-69-7|Drazoxolon

Introduction：Basic information about CAS 5707-69-7|Drazoxolon, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Chemical & Physical Properties
3. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
4. Safety Information
5. Synonyms

Common Name	Drazoxolon
CAS Number	5707-69-7	Molecular Weight	237.64200
Density	1.45g/cm3	Boiling Point	321.8ºC at 760 mmHg
Molecular Formula	C₁₀H₈ClN₃O₂	Melting Point	167ºC
MSDS	USA	Flash Point	>100 °C
Symbol	GHS06, GHS09	Signal Word	Danger

Names

Name	drazoxolon
Synonym	More Synonyms

Chemical & Physical Properties

Density	1.45g/cm3
Boiling Point	321.8ºC at 760 mmHg
Melting Point	167ºC
Molecular Formula	C₁₀H₈ClN₃O₂
Molecular Weight	237.64200
Flash Point	>100 °C
Exact Mass	237.03100
PSA	63.05000
LogP	1.54920
Index of Refraction	1.648
InChIKey	ZRGHYHHYHYAJBT-UHFFFAOYSA-N
SMILES	Cc1[nH]oc(=O)c1N=Nc1ccccc1Cl

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: NY2800000

CHEMICAL NAME :: 4,5-Isoxazoledione, 3-methyl-, 4-((o-chlorophenyl)hydrazone)

CAS REGISTRY NUMBER :: 5707-69-7

LAST UPDATED :: 199204

DATA ITEMS CITED :: 10

MOLECULAR FORMULA :: C10-H8-Cl-N3-O2

MOLECULAR WEIGHT :: 237.66

WISWESSER LINE NOTATION :: T5NOVYJ DUNMR BG& E1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 126 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 7,481,1969

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 20 mg/kg

TOXIC EFFECTS :: Brain and Coverings - recordings from specific areas of CNS Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - other changes

REFERENCE :: FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 7,481,1969

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 129 mg/kg

TOXIC EFFECTS :: Brain and Coverings - recordings from specific areas of CNS Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - other changes

REFERENCE :: FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 7,481,1969

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 20 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 7,481,1969

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Mammal - cat

DOSE/DURATION :: 50 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 7,481,1969

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 100 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 7,481,1969

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 20 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 7,481,1969

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 12500 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 7,481,1969

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Bird - pigeon

DOSE/DURATION :: 12 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 7,481,1969

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Bird - chicken

DOSE/DURATION :: 100 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 7,481,1969

Safety Information

Symbol	GHS06, GHS09
Signal Word	Danger
Hazard Statements	H301-H410
Precautionary Statements	P273-P301 + P310-P501
Personal Protective Equipment	Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges
Hazard Codes	T,N
Risk Phrases	25-50/53
Safety Phrases	22-24-36/37-45-60-61
RIDADR	2588
WGK Germany	3
RTECS	NY2800000
Packaging Group	III
Hazard Class	6.1(b)

Synonyms

Drazoxolone

(EZ)-4-(2-chlorophenylhydrazono)-3-methylisoxazol-5(4H)-one

Caswell No. 207C

(EZ)-4-(2-chlorophenylhydrazono)-3-methyl-1,2-oxazol-5(4H)-one

(4Z)-4-[(2-chlorophenyl)hydrazinylidene]-3-methyl-1,2-oxazol-5-one

Ganocide

MFCD00144225

Sopracol 781

Saisan

EINECS 227-197-8

Sopracol

Mil-col

(4Ξ)-4-[(2-chlorophenyl)hydrazinylidene]-3-methyl-1,2-oxazol-5(4H)-one

DRAZOXOLON

3-methyl-4,5-isoxazoledione 4-[(2-chlorophenyl)hydrazone]

PP781

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