Introduction：Basic information about CAS 146369-65-5|TIPP, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | TIPP |
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| CAS Number | 146369-65-5 | Molecular Weight | 634.72 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C37H38N4O6 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | (2S)-2-[[(2S)-2-[[(3S)-2-[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]-3,4-dihydro-1H-isoquinoline-3-carbonyl]amino]-3-phenylpropanoyl]amino]-3-phenylpropanoic acid |
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| Synonym | More Synonyms |
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TIPP BiologicalActivity
| Description | TIPP is a potent and selective δ-opioid antagonist with a Ki value of 1.22 nM[1]. |
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| Related Catalog | Signaling Pathways >>GPCR/G Protein >>Opioid ReceptorSignaling Pathways >>Neuronal Signaling >>Opioid ReceptorResearch Areas >>Neurological Disease |
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| References | [1]. Schiller PW, et al. The TIPP opioid peptide family: development of delta antagonists, delta agonists, and mixed mu agonist/delta antagonists. Biopolymers. 1999;51(6):411-25. |
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Chemical & Physical Properties
| Molecular Formula | C37H38N4O6 |
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| Molecular Weight | 634.72 |
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| Exact Mass | 634.27900 |
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| PSA | 162.06000 |
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| LogP | 4.17510 |
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| InChIKey | JYOUATXRHWNDDW-YRCZKMHPSA-N |
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| SMILES | NC(Cc1ccc(O)cc1)C(=O)N1Cc2ccccc2CC1C(=O)NC(Cc1ccccc1)C(=O)NC(Cc1ccccc1)C(=O)O |
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Synonyms
| Tyr-tic-phe-phe-OH |
| H-Tyr-Tic-Phe-Phe-OH |
| L-Phenylalanine,L-tyrosyl-L-1,2,3,4-tetrahydro-3-isoquinolinecarbonyl-L-phenylalanyl |
| TIPP |
