CAS 512-15-2|CYCLOPENTOLATE

Introduction:Basic information about CAS 512-15-2|CYCLOPENTOLATE, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameCYCLOPENTOLATE
CAS Number512-15-2Molecular Weight291.38500
Density1.136g/cm3Boiling Point409.7ºC at 760mmHg
Molecular FormulaC17H25NO3Melting Point/
MSDS/Flash Point201.5ºC

Names

Namecyclopentolate
SynonymMore Synonyms

CYCLOPENTOLATE BiologicalActivity

DescriptionCyclopentolate (DL-Cyclopentolate) is an Atropine-like muscarinic receptors antagonist with a pKB value of 7.8 (on the circular ciliary muscle). Cyclopentolate is an anti-muscarinic agent commonly used in the ophthalmologic practice[1][2].
Related CatalogSignaling Pathways >>Neuronal Signaling >>mAChRSignaling Pathways >>GPCR/G Protein >>mAChRResearch Areas >>Neurological Disease
In VivoSurvival in rats pretreated with cyclopentolate (20 mg/kg) is 90%[3].
References

[1]. Öner V, Bulut A, Öter K. The effect of topical anti-muscarinic agents on subfoveal choroidal thickness in healthy adults. Eye (Lond). 2016;30(7):925‐928.

[2]. Ishikawa H, DeSantis L, Patil PN. Selectivity of muscarinic agonists including (+/-)-aceclidine and antimuscarinics on the human intraocular muscles. J Ocul Pharmacol Ther. 1998;14(4):363‐373.

[3]. Öner V, Bulut A, Öter K. The effect of topical anti-muscarinic agents on subfoveal choroidal thickness in healthy adults. Eye (Lond). 2016;30(7):925‐928.

Chemical & Physical Properties

Density1.136g/cm3
Boiling Point409.7ºC at 760mmHg
Molecular FormulaC17H25NO3
Molecular Weight291.38500
Flash Point201.5ºC
Exact Mass291.18300
PSA49.77000
LogP2.18010
Index of Refraction1.555
InChIKeySKYSRIRYMSLOIN-UHFFFAOYSA-N
SMILESCN(C)CCOC(=O)C(c1ccccc1)C1(O)CCCC1

Safety Information

HS Code2922509090

Customs

HS Code2922509090
Summary2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Synonyms

Ocu-Pentolate
Cyclogyl
Cylate
Mydrilate
2-(dimethylamino)ethyl 2-(1-hydroxycyclopentyl)-2-phenylacetate
Cyclopentoiate
Ciclopentolato
Cyclopentolatum
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