Introduction：Basic information about CAS 68206-94-0|Cloricromene, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Cloricromene |
|---|
| CAS Number | 68206-94-0 | Molecular Weight | 395.87700 |
|---|
| Density | 1.189g/cm3 | Boiling Point | 514.1ºC at 760mmHg |
|---|
| Molecular Formula | C20H26ClNO5 | Melting Point | 221-222.3ºC |
|---|
| MSDS | Chinese | Flash Point | 264.7ºC |
|---|
Names
| Name | ethyl 2-[8-chloro-3-[2-(diethylamino)ethyl]-4-methyl-2-oxochromen-7-yl]oxyacetate |
|---|
| Synonym | More Synonyms |
|---|
Cloricromene BiologicalActivity
| Description | Cloricromen (Cloricromene) is a platelet aggregation inhibitor. Cloricromen can inhibit platelet aggregation in man and in experimental thrombosis[1]. |
|---|
| Related Catalog | Research Areas >>Cardiovascular Disease |
|---|
| References | [1]. G Orefice, et al. No effect of cloricromen on some coagulation parameters in patients with ischaemic cerebrovascular disease. J Int Med Res. 1994 Sep-Oct;22(5):287-91. |
|---|
Chemical & Physical Properties
| Density | 1.189g/cm3 |
|---|
| Boiling Point | 514.1ºC at 760mmHg |
|---|
| Melting Point | 221-222.3ºC |
|---|
| Molecular Formula | C20H26ClNO5 |
|---|
| Molecular Weight | 395.87700 |
|---|
| Flash Point | 264.7ºC |
|---|
| Exact Mass | 395.15000 |
|---|
| PSA | 68.98000 |
|---|
| LogP | 3.58100 |
|---|
| Appearance of Characters | solid | white |
|---|
| Index of Refraction | 1.532 |
|---|
| InChIKey | GYNNRVJJLAVVTQ-UHFFFAOYSA-N |
|---|
| SMILES | CCOC(=O)COc1ccc2c(C)c(CCN(CC)CC)c(=O)oc2c1Cl |
|---|
| Storage condition | 2-8°C |
|---|
| Water Solubility | DMSO: 17 mg/mL |
|---|
Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- AF8970000
- CHEMICAL NAME :
- Acetic acid, ((8-chloro-3-(2-(diethylamino)ethyl)-4-methyl-2-oxo-2 H-1-benzopyran-7-yl)o xy)-, ethyl ester
- CAS REGISTRY NUMBER :
- 68206-94-0
- LAST UPDATED :
- 199706
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C20-H26-Cl-N-O5
- MOLECULAR WEIGHT :
- 395.92
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1250 mg/kg
- TOXIC EFFECTS :
- Blood - hemorrhage
- REFERENCE :
- CDREEA Cardiovascular Drug Reviews. (Raven Press, 1185 Avenue of the Americas, New York, NY 10036) V.6- 1988- Volume(issue)/page/year: 9,357,1991
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 10 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CDREEA Cardiovascular Drug Reviews. (Raven Press, 1185 Avenue of the Americas, New York, NY 10036) V.6- 1988- Volume(issue)/page/year: 9,357,1991
|
Safety Information
| Hazard Codes | Xn |
|---|
| Risk Phrases | R22 |
|---|
| WGK Germany | 3 |
|---|
| RTECS | AF8970000 |
|---|
Synonyms
| MFCD06409251 |
| Cloricromen |
| Cloricromenum [Latin] |
| Cloricromeno [Spanish] |
| Proendotel |
| Cloricromen (INN) |
| Cloricromene |
| Cloricromene [French] |
| 8-Chlorocarbochromen |
| AD 6 (pharmaceutical) |
