CAS 119018-29-0|Glimepiride sulfonamide

Introduction：Basic information about CAS 119018-29-0|Glimepiride sulfonamide, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameGlimepiride sulfonamide
CAS Number119018-29-0Molecular Weight351.421
Density1.3±0.1 g/cm3Boiling Point/
Molecular FormulaC16H21N3O4SMelting Point177-179?C
MSDS/Flash Point/

Names

Name4-[2-[(3-Ethyl-4-methyl-2-oxo-3-pyrrolin-1-yl)carboxamido]ethyl]benzenesulfonamide
SynonymMore Synonyms

Glimepiride sulfonamide BiologicalActivity

DescriptionGlimepiride sulfonamide is a intermediate, and can be used to synthesize Glimepiride (HY-B0104) (antidiabetic agent)[1].
Related CatalogResearch Areas >>InfectionSignaling Pathways >>Others >>Others
References

[1]. Parmar HS, et al. Study on gluco-regulatory potential of glimepiride sulfonamide using in silico, in vitro and in vivo approaches. Curr Pharm Des. 2014;20(32):5212-7.  

Chemical & Physical Properties

Density1.3±0.1 g/cm3
Melting Point177-179?C
Molecular FormulaC16H21N3O4S
Molecular Weight351.421
Exact Mass351.125275
PSA117.95000
LogP0.43
Index of Refraction1.588
InChIKeyAJEMFZRCUKJSES-UHFFFAOYSA-N
SMILESCCC1=C(C)CN(C(=O)NCCc2ccc(S(N)(=O)=O)cc2)C1=O
Storage conditionRefrigerator

Safety Information

Hazard CodesXi
Risk PhrasesR52/53
Safety Phrases61
RIDADRNONH for all modes of transport
HS Code2935009090

Customs

HS Code2935009090
Summary2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%

Articles1

More Articles
Simultaneous determination of Glimepiride and Metformin hydrochloride impurities in sustained release pharmaceutical drug product by HPLC. Pawar, Shraddha, et al.

Der Pharma Chemica 2.4 , 157-168, (2010)

Synonyms

3-Ethyl-4-methyl-2-oxo-N-[2-(4-sulfamoylphenyl)ethyl]-2,5-dihydro-1H-pyrrole-1-carboxamide
SulfonamideofGlimepiride
1H-Pyrrole-1-carboxamide, N-[2-[4-(aminosulfonyl)phenyl]ethyl]-3-ethyl-2,5-dihydro-4-methyl-2-oxo-
MFCD08460214
GliMepiride Related CoMpound B
EINECS 411-850-0
Glimepiride sulfonamide
3-Ethyl-4-methyl-2-oxo-N-[2-(4-sulfamoylphenyl)ethyl]-2,5-dihydro-1H-pyrrol-1-carboxamid
4-[2-(3-ethyl-4-methyl-2-oxy-3-pyrrolinyl-1-methylamide)-ethyl]benzenesulfonamide
CAS 902248-99-1|6-ethoxy-N-(2-pyridinylmethyl)-2-naphthalenesulfonamide
CAS 513246-79-2|(R)-2-(3-Bromophenyl)-4-methylpentanoic acid
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