Introduction：Basic information about CAS 1188-37-0|N-Acetyl-L-glutamic acid, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | N-Acetyl-L-glutamic acid |
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| CAS Number | 1188-37-0 | Molecular Weight | 189.166 |
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| Density | 1.4±0.1 g/cm3 | Boiling Point | 495.9±35.0 °C at 760 mmHg |
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| Molecular Formula | C7H11NO5 | Melting Point | 194-196 °C(lit.) |
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| MSDS | ChineseUSA | Flash Point | 253.7±25.9 °C |
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Names
| Name | N-acetyl-L-glutamate(2-) |
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| Synonym | More Synonyms |
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N-Acetyl-L-glutamic acid BiologicalActivity
| Description | N-Acetyl-L-glutamic acid, a N-acyl-L-amino acid, is a component of animal cell culturing media. N-Acetyl-L-glutamic acid is a metabolite of Saccharomyces cerevisiae and human[1]. |
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| Related Catalog | Research Areas >>Metabolic Disease |
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| References | [1]. M Hashimoto, et al. Animal cell culturing media containing N-acetyl-L-glutamic acid. Patent. |
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Chemical & Physical Properties
| Density | 1.4±0.1 g/cm3 |
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| Boiling Point | 495.9±35.0 °C at 760 mmHg |
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| Melting Point | 194-196 °C(lit.) |
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| Molecular Formula | C7H11NO5 |
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| Molecular Weight | 189.166 |
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| Flash Point | 253.7±25.9 °C |
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| Exact Mass | 189.063721 |
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| PSA | 103.70000 |
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| LogP | -2.24 |
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| Vapour Pressure | 0.0±2.7 mmHg at 25°C |
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| Index of Refraction | 1.502 |
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| InChIKey | RFMMMVDNIPUKGG-YFKPBYRVSA-N |
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| SMILES | CC(=O)NC(CCC(=O)O)C(=O)O |
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| Storage condition | 2~8°C |
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| Water Solubility | 2.7 g/100 mL (20 ºC) |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- LZ9725000
- CHEMICAL NAME :
- L-Glutamic acid, N-acetyl-
- CAS REGISTRY NUMBER :
- 1188-37-0
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C7-H11-N-O5
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >7 gm/kg
- TOXIC EFFECTS :
- Brain and Coverings - changes in circulation (hemorrhage, thrombosis, etc.) Lungs, Thorax, or Respiration - other changes Blood - hemorrhage
- REFERENCE :
- TOVEFN Toksikologicheskii Vestnik. (18-20 Vadkovskii per. Moscow, 101479, Russia) History Unknown Volume(issue)/page/year: (3),36,1995
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 6838 mg/kg
- TOXIC EFFECTS :
- Brain and Coverings - changes in circulation (hemorrhage, thrombosis, etc.) Lungs, Thorax, or Respiration - other changes Blood - hemorrhage
- REFERENCE :
- TOVEFN Toksikologicheskii Vestnik. (18-20 Vadkovskii per. Moscow, 101479, Russia) History Unknown Volume(issue)/page/year: (3),36,1995
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 711 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea
- REFERENCE :
- TOVEFN Toksikologicheskii Vestnik. (18-20 Vadkovskii per. Moscow, 101479, Russia) History Unknown Volume(issue)/page/year: (3),36,1995
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Safety Information
| Hazard Codes | Xi |
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| Safety Phrases | S24/25 |
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| RIDADR | NONH for all modes of transport |
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| WGK Germany | 2 |
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| RTECS | LZ9725000 |
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| HS Code | 29241900 |
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Customs
| HS Code | 2924199090 |
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| Summary | 2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
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Synonyms
| (2S)-2-(acetylamino)pentanedioic acid |
| EINECS 214-708-4 |
| N-Acetyl-L-glutamicacid |
| AC-GLU-OH |
| N-acetyl-L-glutamate |
| (S)-2-acetamidopentanedioic acid |
| N-ACETYL-L-GLU |
| N-AC-L-GLU |
| MFCD00002802 |
| N-Acetyl-L-Glutamic |
| N-Acetyl-L-glutamic Acid |
| N-acetyl-Glu |
| acetylglutamicacid |
| Acetyl-L-glutamic acid |
| 2-(acetylamino)pentanedioic acid |
| L-Glutamic acid, N-acetyl- |
| NAcGlu |
| n-acetylglutamic |
| N-Acetylglutamate |
| n-acetylglutamicacid |
| l-glutamicaci |
