CAS 154674-81-4|Ac-Tyr-Val-Ala-Asp-2,6-dimethylbenzoyloxymethylketone

Introduction：Basic information about CAS 154674-81-4|Ac-Tyr-Val-Ala-Asp-2,6-dimethylbenzoyloxymethylketone, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. BiologicalActivity
3. Chemical & Physical Properties
4. Synonyms

Common Name	Ac-Tyr-Val-Ala-Asp-2,6-dimethylbenzoyloxymethylketone
CAS Number	154674-81-4	Molecular Weight	654.707
Density	1.3±0.1 g/cm3	Boiling Point	1029.6±65.0 °C at 760 mmHg
Molecular Formula	C₃₃H₄₂N₄O₁₀	Melting Point	/
MSDS	/	Flash Point	576.5±34.3 °C

Names

Name	ac-yvad-2,6-dimethylbenzoyloxymethylketone
Synonym	More Synonyms

BiologicalActivity

Description	Ac-YVAD-AOM is the inhibitor of caspase-1 that shows antitumor activity[1].
Related Catalog	Research Areas >>CancerSignaling Pathways >>Apoptosis >>Caspase
References	[1]. S Schlosser, et al. Inhibition of caspase-1 induces cell death in pancreatic carcinoma cells and potentially modulates expression levels of bcl-2 family proteins. FEBS Lett. 2001 Feb 23;491(1-2):104-8.

Chemical & Physical Properties

Density	1.3±0.1 g/cm3
Boiling Point	1029.6±65.0 °C at 760 mmHg
Molecular Formula	C₃₃H₄₂N₄O₁₀
Molecular Weight	654.707
Flash Point	576.5±34.3 °C
Exact Mass	654.290100
PSA	217.30000
LogP	4.77
Vapour Pressure	0.0±0.3 mmHg at 25°C
Index of Refraction	1.566
InChIKey	LOACDHZQOPEFKK-NFJAKAEBSA-N
SMILES	CC(=O)NC(Cc1ccc(O)cc1)C(=O)NC(C(=O)NC(C)C(=O)NC(CC(=O)O)C(=O)COC(=O)c1c(C)cccc1C)C(C)C

Synonyms

pase-1 inhibitor v

bacmk

N-Acetyl-L-tyrosyl-L-valyl-N-{(2S)-1-carboxy-4-[(2,6-dimethylbenzoyl)oxy]-3-oxobutan-2-yl}-L-alaninamide

N-Acetyl-L-tyrosyl-L-valyl-N-{(2S)-1-carboxy-4-[(2,6-dimethylbenzoyl)oxy]-3-oxo-2-butanyl}-L-alaninamide

ice inhibitor iv

pase inhibitor iv

L-Alaninamide, N-acetyl-L-tyrosyl-L-valyl-N-[(1S)-1-(carboxymethyl)-3-[(2,6-dimethylbenzoyl)oxy]-2-oxopropyl]-

pase-1 inhibitor iv

ac-yvad-aom

boc-d-cmk

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