Introduction：Basic information about CAS 557756-85-1|Fmoc-NH-PEG4-CH2CH2COOH, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Fmoc-NH-PEG4-CH2CH2COOH |
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| CAS Number | 557756-85-1 | Molecular Weight | 487.54200 |
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| Density | 1.219 | Boiling Point | / |
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| Molecular Formula | C26H33NO8 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | 1-(9H-Fluoren-9-yl)-3-oxo-2,7,10,13,16-pentaoxa-4-azanonadecan-19-oic acid |
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| Synonym | More Synonyms |
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Fmoc-NH-PEG4-CH2CH2COOH BiologicalActivity
| Description | Fmoc-NH-PEG4-CH2CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>Antibody-drug Conjugate >>ADC Linker |
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| Target | Cleavable |
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| In Vitro | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. |
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| References | [1]. Cai P, et al. Synthesis of C3-Alkylated Indoles on DNA via Indolyl Alcohol Formation Followed by Metal-FreeTransfer Hydrogenation. Org Lett. 2019 Aug 14. |
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Chemical & Physical Properties
| Density | 1.219 |
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| Molecular Formula | C26H33NO8 |
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| Molecular Weight | 487.54200 |
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| Exact Mass | 487.22100 |
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| PSA | 112.55000 |
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| LogP | 3.45710 |
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| InChIKey | NUHRPLKTAAVHCZ-UHFFFAOYSA-N |
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| SMILES | O=C(O)CCOCCOCCOCCOCCNC(=O)OCC1c2ccccc2-c2ccccc21 |
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Safety Information
Synonyms
| Fmoc-15-Amino-4,7,10,13-Tetraoxapentadecanoic Acid |
| 5,8,11,14-Tetraoxa-2-azaheptadecanedioic acid 1-(9H-fluoren-9-ylmethyl) ester |
| Fmoc-PEG4-propionic acid |
