Introduction：Basic information about CAS 153039-17-9|4-Boc-amino-2,2-dimethylbutyric acid, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 4-Boc-amino-2,2-dimethylbutyric acid |
|---|
| CAS Number | 153039-17-9 | Molecular Weight | 231.28900 |
|---|
| Density | 1.065g/cm3 | Boiling Point | 369.9ºC at 760mmHg |
|---|
| Molecular Formula | C11H21NO4 | Melting Point | / |
|---|
| MSDS | / | Flash Point | 177.5ºC |
|---|
Names
| Name | 4-boc-amino-2,2-dimethylbutyric acid |
|---|
| Synonym | More Synonyms |
|---|
4-Boc-amino-2,2-dimethylbutyric acid BiologicalActivity
| Description | 4-Boc-amino-22-dimethylbutyric acid is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|
| Related Catalog | Research Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker |
|---|
| Target | Alkyl/ether |
|---|
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
|---|
| References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
|---|
Chemical & Physical Properties
| Density | 1.065g/cm3 |
|---|
| Boiling Point | 369.9ºC at 760mmHg |
|---|
| Molecular Formula | C11H21NO4 |
|---|
| Molecular Weight | 231.28900 |
|---|
| Flash Point | 177.5ºC |
|---|
| Exact Mass | 231.14700 |
|---|
| PSA | 75.63000 |
|---|
| LogP | 2.40290 |
|---|
| Vapour Pressure | 1.74E-06mmHg at 25°C |
|---|
| Index of Refraction | 1.463 |
|---|
| InChIKey | TWMVVJUXUMIAAJ-UHFFFAOYSA-N |
|---|
| SMILES | CC(C)(C)OC(=O)NCCC(C)(C)C(=O)O |
|---|
Synonyms
| 1-Boc-3-Carbamoylpiperazine |
