Introduction：Basic information about CAS 83928-76-1|gepirone, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | gepirone |
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| CAS Number | 83928-76-1 | Molecular Weight | 359.47 |
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| Density | 1.1±0.1 g/cm3 | Boiling Point | 562.3±60.0 °C at 760 mmHg |
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| Molecular Formula | C19H29N5O2 | Melting Point | / |
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| MSDS | / | Flash Point | 293.8±32.9 °C |
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Names
| Name | 4,4-Dimethyl-1-(4-(4-(pyrimidin-2-yl)piperazin-1-yl)butyl)piperidine-2,6-dione |
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| Synonym | More Synonyms |
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gepirone BiologicalActivity
| Description | Gepirone is a selectively and affinitive 5-HT1A agonist. Gepirone binds selectively to 5-HT1A receptor binding site. Gepirone acts as an antidepressant agent can be used for anxiety and major depressive disorder research[1]. |
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| Related Catalog | Research Areas >>OthersSignaling Pathways >>GPCR/G Protein >>5-HT ReceptorSignaling Pathways >>Neuronal Signaling >>5-HT Receptor |
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| Target | 5-HT1A Receptor |
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| References | [1]. Mendelson SD, et al. Effects of 5-HT1A selective anxiolytics on lordosis behavior: interactions with progesterone. Eur J Pharmacol. 1986 Dec 16;132(2-3):323-6. [2]. Blier P, et al. Modification of 5-HT neuron properties by sustained administration of the 5-HT1A agonist gepirone: electrophysiological studies in the rat brain. Synapse. 1987;1(5):470-80. |
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Chemical & Physical Properties
| Density | 1.1±0.1 g/cm3 |
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| Boiling Point | 562.3±60.0 °C at 760 mmHg |
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| Molecular Formula | C19H29N5O2 |
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| Molecular Weight | 359.47 |
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| Flash Point | 293.8±32.9 °C |
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| Exact Mass | 359.232117 |
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| PSA | 69.64000 |
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| LogP | 2.95 |
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| Vapour Pressure | 0.0±1.5 mmHg at 25°C |
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| Index of Refraction | 1.542 |
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| InChIKey | QOIGKGMMAGJZNZ-UHFFFAOYSA-N |
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| SMILES | CC1(C)CC(=O)N(CCCCN2CCN(c3ncccn3)CC2)C(=O)C1 |
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Safety Information
Customs
| HS Code | 2933990090 |
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| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Synonyms
| 3,3-Dimethyl-1-[4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl]glutarimide |
| gepirone |
| 4,4-Dimethyl-1-[4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl]-2,6-piperidinedione |
| 4,4-Dimethyl-1-{4-[4-(pyrimidin-2-yl)piperazin-1-yl]butyl}piperidine-2,6-dione |
| 2,6-Piperidinedione, 4,4-dimethyl-1-[4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl]- |
| 4,4-Dimethyl-1-{4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl}-2,6-piperidinedione |
| 4,4-dimethyl-1-[4-(4-pyrimidin-2-ylpiperazin-1-yl)butyl]piperidine-2,6-dione |
