Introduction：Basic information about CAS 1243-33-0|Mefeclorazine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Mefeclorazine |
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| CAS Number | 1243-33-0 | Molecular Weight | 360.87800 |
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| Density | 1.16g/cm3 | Boiling Point | 490.1ºC at 760 mmHg |
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| Molecular Formula | C20H25ClN2O2 | Melting Point | / |
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| MSDS | / | Flash Point | 250.2ºC |
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Names
| Name | 1-(2-chlorophenyl)-4-[2-(3,4-dimethoxyphenyl)ethyl]piperazine |
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| Synonym | More Synonyms |
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Chemical & Physical Properties
| Density | 1.16g/cm3 |
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| Boiling Point | 490.1ºC at 760 mmHg |
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| Molecular Formula | C20H25ClN2O2 |
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| Molecular Weight | 360.87800 |
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| Flash Point | 250.2ºC |
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| Exact Mass | 360.16000 |
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| PSA | 24.94000 |
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| LogP | 3.72480 |
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| Vapour Pressure | 9.43E-10mmHg at 25°C |
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| Index of Refraction | 1.57 |
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| InChIKey | PJDRMPCBIWKBJA-UHFFFAOYSA-N |
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| SMILES | COc1ccc(CCN2CCN(c3ccccc3Cl)CC2)cc1OC |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- TL2803000
- CHEMICAL NAME :
- Piperazine, 1-(o-chlorophenyl)-4-(3,4-dimethoxyphenethyl)-
- CAS REGISTRY NUMBER :
- 1243-33-0
- BEILSTEIN REFERENCE NO. :
- 0627902
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C20-H25-Cl-N2-O2
- MOLECULAR WEIGHT :
- 360.92
- WISWESSER LINE NOTATION :
- T6N DNTJ A2R CO1 DO1& DR CG
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >2 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- PSCBAY Psychopharmacology Service Center, Bulletin. (Bethesda, MD) V.1-3, 1961-65. For publisher information, see PSYBB9. Volume(issue)/page/year: 2,17,1963
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 100 mg/kg
- TOXIC EFFECTS :
- Autonomic Nervous System - central sympatholytic Vascular - BP elevation not characterized in autonomic section Lungs, Thorax, or Respiration - bronchiolar dilation
- REFERENCE :
- JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 8,104,1965
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 55 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 133,29,1961
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Safety Information
Customs
| HS Code | 2933599090 |
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| Summary | 2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Synonyms
| 1-(2-chloro-phenyl)-4-(3,4-dimethoxy-phenethyl)-piperazine |
| Mefeclorazina [INN-Spanish] |
| 4-<2-Chlor-phenyl>-1-<3,4-dimethoxy-phenethyl>-piperazin |
| 1-o-Chlorophenyl-4-(3,4-dimethoxyphenethyl)piperazine |
| Mefeclorazinum [INN-Latin] |
| 1-(2-Chlorphenyl)-4-(3,4-dimethoxyphenethyl)piperazine |
| N-(Dimethoxy-3,4-phenethyl),-N'-(chloro-2-phenyl) piperazine |
| Piperazine,1-(o-chlorophenyl)-4-(3,4-dimethoxyphenethyl) |
| Mefeclorazine |
| SD 218-06 |
| Mepheclorazin |
