Introduction：Basic information about CAS 2050-25-1|Diethylene Glycol Monobenzyl Ether, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Diethylene Glycol Monobenzyl Ether |
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| CAS Number | 2050-25-1 | Molecular Weight | 196.243 |
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| Density | 1.1±0.1 g/cm3 | Boiling Point | 311.2±22.0 °C at 760 mmHg |
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| Molecular Formula | C11H16O3 | Melting Point | / |
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| MSDS | ChineseUSA | Flash Point | 142.0±22.3 °C |
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Names
| Name | 2-(2-phenylmethoxyethoxy)ethanol |
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| Synonym | More Synonyms |
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Diethylene Glycol Monobenzyl Ether BiologicalActivity
| Description | Diethylene Glycol Monobenzyl Ether is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker |
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| Target | PEGs |
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| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
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| References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
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Chemical & Physical Properties
| Density | 1.1±0.1 g/cm3 |
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| Boiling Point | 311.2±22.0 °C at 760 mmHg |
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| Molecular Formula | C11H16O3 |
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| Molecular Weight | 196.243 |
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| Flash Point | 142.0±22.3 °C |
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| Exact Mass | 196.109940 |
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| PSA | 38.69000 |
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| LogP | 0.90 |
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| Vapour Pressure | 0.0±0.7 mmHg at 25°C |
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| Index of Refraction | 1.513 |
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| InChIKey | LJVNVNLFZQFJHU-UHFFFAOYSA-N |
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| SMILES | OCCOCCOCc1ccccc1 |
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Safety Information
| Personal Protective Equipment | Eyeshields;Gloves |
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| RIDADR | NONH for all modes of transport |
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| HS Code | 2909499000 |
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Customs
| HS Code | 2909499000 |
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| Summary | 2909499000. ether-alcohols and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:5.5%. General tariff:30.0% |
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Articles1
More Articles
| Synthesis and characterization of star poly(epsilon-caprolactone)-b-poly(ethylene glycol) and poly(L-lactide)-b-poly(ethylene glycol) copolymers: evaluation as drug delivery carriers. Bioconjug. Chem. 19(7) , 1423-9, (2008) Two types of 32 arm star polymers incorporating amphiphilic block copolymer arms have been synthesized and characterized. The first type, stPCL-PEG 32, is composed of a polyamidoamine (PAMAM) dendrime... | |
Synonyms
| Ethanol, 2-[2-(phenylmethoxy)ethoxy]- |
| 2-[2-(Benzyloxy)ethoxy]ethanol |
| Ethanol, 2-[2-(benzyloxy)ethoxy]- |
| Ethanol, 2-[2- (phenylmethoxy)ethoxy]- |
| Diethylene Glycol Monobenzyl Ether |
| MFCD00029649 |
| Ethanol, 2-[2- (benzyloxy)ethoxy]- |
