CAS 536-38-9|2-Bromo-4'-chloroacetophenone

Introduction：Basic information about CAS 536-38-9|2-Bromo-4'-chloroacetophenone, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Chemical & Physical Properties
3. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
4. Safety Information
5. Customs
6. Articles2
7. Synonyms

Common Name	2-Bromo-4'-chloroacetophenone
CAS Number	536-38-9	Molecular Weight	233.490
Density	1.6±0.1 g/cm3	Boiling Point	289.7±15.0 °C at 760 mmHg
Molecular Formula	C₈H₆BrClO	Melting Point	95-99ºC
MSDS	ChineseUSA	Flash Point	129.0±20.4 °C
Symbol	GHS05	Signal Word	Danger

Names

Name	2-Bromo-4’-chloroacetophenone
Synonym	More Synonyms

Chemical & Physical Properties

Density	1.6±0.1 g/cm3
Boiling Point	289.7±15.0 °C at 760 mmHg
Melting Point	95-99ºC
Molecular Formula	C₈H₆BrClO
Molecular Weight	233.490
Flash Point	129.0±20.4 °C
Exact Mass	231.929047
PSA	17.07000
LogP	2.88
Vapour Pressure	0.0±0.6 mmHg at 25°C
Index of Refraction	1.584
InChIKey	FLAYZKKEOIAALB-UHFFFAOYSA-N
SMILES	O=C(CBr)c1ccc(Cl)cc1

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AM5978800

CHEMICAL NAME :: Acetophenone, 2-bromo-4'-chloro-

CAS REGISTRY NUMBER :: 536-38-9

BEILSTEIN REFERENCE NO. :: 0607603

LAST UPDATED :: 199709

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C8-H6-Br-Cl-O

MOLECULAR WEIGHT :: 233.50

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >2 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: MEXPAG Medicina Experimentalis. (Basel, Switzerland) V.1-11, 1959-64; V.18-19, 1968-69. For publisher information, see JNMDBO. Volume(issue)/page/year: 11,137,1964

Safety Information

Symbol	GHS05
Signal Word	Danger
Hazard Statements	H314
Precautionary Statements	P280-P305 + P351 + P338-P310
Personal Protective Equipment	Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
Hazard Codes	C:Corrosive;
Risk Phrases	R22;R34
Safety Phrases	S26-S36/37/39-S45
RIDADR	UN 3261 8/PG 2
WGK Germany	2
RTECS	AM5978800
Packaging Group	III
HS Code	2914399090

Customs

HS Code	2914399090
Summary	2914399090. other aromatic ketones without other oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%

Articles2

Design, synthesis and structure-activity relationship studies of novel and diverse cyclooxygenase-2 inhibitors as anti-inflammatory drugs.

J. Enzyme Inhib. Med. Chem. 29(6) , 846-67, (2014)

Because of the pivotal role of cyclooxygenase (COX) in the inflammatory processes, non-steroidal anti-inflammatory drugs (NSAIDs) that suppress COX activities have been used clinically for the treatme...

Switching reversibility to irreversibility in glycogen synthase kinase 3 inhibitors: clues for specific design of new compounds.

J. Med. Chem. 54 , 4042-56, (2011)

Development of kinase-targeted therapies for central nervous system (CNS) diseases is a great challenge. Glycogen synthase kinase 3 (GSK-3) offers a great potential for severe CNS unmet diseases, bein...

Synonyms

α-Bromo-p-chloroacetophenone

MFCD00000625

Ethanone, 2-bromo-1-(4-chlorophenyl)-

ω-Bromo-4-chloroacetophenone

2-Bromo-4‘-chloroacetophenone

2-Bromo-4'-chloroacetophenone

α-Bromo-4-chloroacetophenone

4'-Chloro-2-Bromoacetophenone

4-Chlorophenacyl Bromide

EINECS 208-631-5

2-Bromo-1-(4-chlorophenyl)ethanone

Ethanone, 2-bromo-1- (4-chlorophenyl)-

α-Bromo-4'-chloroacetophenone

2-bromo-1-(4-chlorophenyl)ethan-1-one

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