CAS 554-62-1|Phytosphingosine
| Common Name | Phytosphingosine | ||
|---|---|---|---|
| CAS Number | 554-62-1 | Molecular Weight | 317.507 |
| Density | 1.0±0.1 g/cm3 | Boiling Point | 483.7±40.0 °C at 760 mmHg |
| Molecular Formula | C18H39NO3 | Melting Point | 102ºC |
| MSDS | USA | Flash Point | 246.4±27.3 °C |
Names
| Name | phytosphingosine |
|---|---|
| Synonym | More Synonyms |
Phytosphingosine BiologicalActivity
| Description | Phytosphingosine is a phospholipid and has anti-cancer activities. Phytosphingosine induces cell apoptosis via caspase 8 activation and Bax translocation in cancer cells[1]. |
|---|---|
| Related Catalog | Signaling Pathways >>Apoptosis >>ApoptosisResearch Areas >>Cancer |
| References | [1]. Moon-Taek Park, et al. Phytosphingosine Induces Apoptotic Cell Death via Caspase 8 Activation and Bax Translocation in Human Cancer Cells. Clin Cancer Res. 2003 Feb;9(2):878-85. |
Chemical & Physical Properties
| Density | 1.0±0.1 g/cm3 |
|---|---|
| Boiling Point | 483.7±40.0 °C at 760 mmHg |
| Melting Point | 102ºC |
| Molecular Formula | C18H39NO3 |
| Molecular Weight | 317.507 |
| Flash Point | 246.4±27.3 °C |
| Exact Mass | 317.292999 |
| PSA | 86.71000 |
| LogP | 5.18 |
| Vapour Pressure | 0.0±2.8 mmHg at 25°C |
| Index of Refraction | 1.490 |
| InChIKey | AERBNCYCJBRYDG-KSZLIROESA-N |
| SMILES | CCCCCCCCCCCCCCC(O)C(O)C(N)CO |
Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Hazard Codes | Xn |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 1.0 |
Articles61
More Articles| 14-3-3-regulated Ca(2+)-dependent protein kinase CPK3 is required for sphingolipid-induced cell death in Arabidopsis. Cell Death Differ. 20(2) , 209-17, (2013) In eukaryotic cells, sphingoid long chain bases (LCBs) such as sphingosine or phytosphingosine (PHS) behave as second messengers involved in various processes including programmed cell death (PCD). In... | |
| Detection of water-soluble disease-associated PrP species in blood and brain of scrapie-infected hamster. Arch. Virol. 160 , 2219-29, (2015) The high-speed supernatant (S(HS)) of scrapie-infected hamster brain homogenate contains a soluble infectivity similar to that of the plasma that escapes leukodepletion and can transmit prion infectio... | |
| Morphogenesis checkpoint kinase Swe1 is the executor of lipolysis-dependent cell-cycle progression. Proc. Natl. Acad. Sci. U. S. A. 112(10) , E1077-85, (2015) Cell growth and division requires the precise duplication of cellular DNA content but also of membranes and organelles. Knowledge about the cell-cycle-dependent regulation of membrane and storage lipi... |
Synonyms
| (2S,3S,4R)-2-Aminooctadecane-1,3,4-triol |
| Phytosphingosine |
| (4R,3S,2S)-2-aminooctadecane-1,3,4-triol |
| PHYTOSPHINGOSINE HYDROCHLORIDE |
| 4-HYDROXYSPHINGANINE |
| 4D-Hydroxysphinganine |
| 1,3,4-Octadecanetriol, 2-amino-, (2S,3S,4R)- |
| (4R)-4-Hydroxysphinganine |
| (2S,3S,4R)-2-Amino-1,3,4-octadecanetriol |
