Introduction：Basic information about CAS 70608-72-9|5-HETE, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 5-HETE |
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| CAS Number | 70608-72-9 | Molecular Weight | 320.466 |
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| Density | 1.0±0.1 g/cm3 | Boiling Point | 487.7±45.0 °C at 760 mmHg |
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| Molecular Formula | C20H32O3 | Melting Point | / |
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| MSDS | / | Flash Point | 262.8±25.2 °C |
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Names
| Name | 5(s)-hete |
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| Synonym | More Synonyms |
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5-HETE BiologicalActivity
| Description | 5(S)-HETE is an endogenous metabolite present in Blood that can be used for the research of Rheumatoid Arthritis, Rhinitis and Asthma[1][2]. |
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| Related Catalog | Research Areas >>Inflammation/Immunology |
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| In Vitro | Endogenous metabolites is defined as those that are annotated by Kyoto Encyclopedia of Genes and Genomes as substrates or products of the ~1900 metabolic enzymes encoded in our genome. It is clear in the body of literature that there are documented toxic properties for many of these metabolites[1]. |
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| References | [1]. Lee N, et al. Endogenous toxic metabolites and implications in cancer therapy. Oncogene. 2020 Aug;39(35):5709-5720. [2]. Chavis C, et al. A method for the measurement of plasma hydroxyeicosatetraenoic acid levels. Anal Biochem. 1999 Jun 15;271(1):105-8. |
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Chemical & Physical Properties
| Density | 1.0±0.1 g/cm3 |
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| Boiling Point | 487.7±45.0 °C at 760 mmHg |
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| Molecular Formula | C20H32O3 |
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| Molecular Weight | 320.466 |
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| Flash Point | 262.8±25.2 °C |
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| Exact Mass | 320.235138 |
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| PSA | 57.53000 |
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| LogP | 5.56 |
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| Vapour Pressure | 0.0±2.8 mmHg at 25°C |
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| Index of Refraction | 1.514 |
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| InChIKey | KGIJOOYOSFUGPC-HJNFCQDVSA-N |
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| SMILES | CCCCCC=CCC=CCC=CC=CC(O)CCCC(=O)O |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- JX3873000
- CHEMICAL NAME :
- 6,8,11,14-Eicosatetraenoic acid, 5-hydroxy-, (S-(E,Z,Z,Z))-
- CAS REGISTRY NUMBER :
- 70608-72-9
- LAST UPDATED :
- 199712
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C20-H32-O3
- MOLECULAR WEIGHT :
- 320.52
HEALTH HAZARD DATAACUTE TOXICITY DATAMUTATION DATA - TYPE OF TEST :
- DNA damage
- TEST SYSTEM :
- Human Lymphocyte
- DOSE/DURATION :
- 5 umol/L
- REFERENCE :
- CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980- Volume(issue)/page/year: 10,1029,1989
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Safety Information
| Hazard Codes | F,Xi |
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| Risk Phrases | 11-36/37/38 |
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| RIDADR | UN 1170 3/PG 2 |
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Synonyms
| 5-hydroxy-6,8,11,14-eicosatetraenoicacid |
| 5(S)-HETE |
| [S-(E,Z,Z,Z)]-5-Hydroxy-6,8,11,14-eicosatetraenoic Acid |
| 5-Hpete |
| 5-HETE |
| 5-Hydroxyicosatetraenoic acid |
| (5S,6E,8Z,11Z,14Z)-5-Hydroxyicosa-6,8,11,14-tetraenoic acid |
| (5S,6E,8Z,11Z,14Z)-5-Hydroxy-6,8,11,14-icosatetraenoic acid |
| 5-hydroxyeicosatetraenoicacid |
| 6,8,11,14-Eicosatetraenoic acid, 5-hydroxy-, (5S,6E,8Z,11Z,14Z)- |
| (S)-5-Hydroxy-6-trans-8,11,14-cis-eicosatetraenoic Acid |
| (5S,6E,8Z,11Z,14Z)-5-Hydroxy-6,8,11,14-eicosatetraenoic acid |
| 5-Hydroxyeicosatetraenoate |
