Introduction:Basic information about CAS 1163135-95-2|(5E)-BiMatoprost, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | (5E)-BiMatoprost |
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| CAS Number | 1163135-95-2 | Molecular Weight | 415.57 |
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| Density | 1.1±0.1 g/cm3 | Boiling Point | 629.8±55.0 °C at 760 mmHg |
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| Molecular Formula | C25H37NO4 | Melting Point | / |
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| MSDS | / | Flash Point | 334.7±31.5 °C |
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Names
| Name | 5-trans-17-phenyl trinor Prostaglandin F2.α. ethyl amide |
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| Synonym | More Synonyms |
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(5E)-BiMatoprost BiologicalActivity
| Description | 5,6-trans-Bimatoprost is the inactive isomer of Bimatoprost (HY-B0191), and can be used as an experimental control. Bimatoprost is a prostaglandin analogue that can be used in studies of ocular hypertension and glaucoma and also has anti-fat formation effects. |
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| Related Catalog | Research Areas >>CancerResearch Areas >>EndocrinologySignaling Pathways >>Others >>Others |
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| References | [1]. Park J, et al. Changes to upper eyelid orbital fat from use of topical bimatoprost, travoprost, and latanoprost. Jpn J Ophthalmol. 2011 Jan;55(1):22-7. [2]. Filippopoulos T, et al. Periorbital changes associated with topical bimatoprost. Ophthal Plast Reconstr Surg. 2008 Jul-Aug;24(4):302-7. |
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Chemical & Physical Properties
| Density | 1.1±0.1 g/cm3 |
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| Boiling Point | 629.8±55.0 °C at 760 mmHg |
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| Molecular Formula | C25H37NO4 |
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| Molecular Weight | 415.57 |
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| Flash Point | 334.7±31.5 °C |
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| Exact Mass | 415.272247 |
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| PSA | 89.79000 |
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| LogP | 1.98 |
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| Vapour Pressure | 0.0±1.9 mmHg at 25°C |
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| Index of Refraction | 1.591 |
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Synonyms
| 4-Androstene-3,17-dione-19-ol |
| 15R-bimatoprost |
| 19-hydroxyandrostenedione |
| 4-androsten-19-ol-3,17-dione |
| (5E)-7-{(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-penten-1-yl]cyclopentyl}-N-ethyl-5-heptenamide |
| (5E)-7-{(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenylpent-1-en-1-yl]cyclopentyl}-N-ethylhept-5-enamide |
| 19-Hydroxyandrostendione |
| 5-Heptenamide, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-penten-1-yl]cyclopentyl]-N-ethyl-, (5E)- |
| 19-Hydroxy-androst-4-en-3,17-dion |
| 15-epi-bimatoprost |
| 19-Hydroxy-4-androstene-3,17-dione |
| 5-trans bimatoprost |