CAS 1163135-95-2|(5E)-BiMatoprost

Introduction:Basic information about CAS 1163135-95-2|(5E)-BiMatoprost, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Name(5E)-BiMatoprost
CAS Number1163135-95-2Molecular Weight415.57
Density1.1±0.1 g/cm3Boiling Point629.8±55.0 °C at 760 mmHg
Molecular FormulaC25H37NO4Melting Point/
MSDS/Flash Point334.7±31.5 °C

Names

Name5-trans-17-phenyl trinor Prostaglandin F2.α. ethyl amide
SynonymMore Synonyms

(5E)-BiMatoprost BiologicalActivity

Description5,6-trans-Bimatoprost is the inactive isomer of Bimatoprost (HY-B0191), and can be used as an experimental control. Bimatoprost is a prostaglandin analogue that can be used in studies of ocular hypertension and glaucoma and also has anti-fat formation effects.
Related CatalogResearch Areas >>CancerResearch Areas >>EndocrinologySignaling Pathways >>Others >>Others
References

[1]. Park J, et al. Changes to upper eyelid orbital fat from use of topical bimatoprost, travoprost, and latanoprost. Jpn J Ophthalmol. 2011 Jan;55(1):22-7.  

[2]. Filippopoulos T, et al. Periorbital changes associated with topical bimatoprost. Ophthal Plast Reconstr Surg. 2008 Jul-Aug;24(4):302-7.  

Chemical & Physical Properties

Density1.1±0.1 g/cm3
Boiling Point629.8±55.0 °C at 760 mmHg
Molecular FormulaC25H37NO4
Molecular Weight415.57
Flash Point334.7±31.5 °C
Exact Mass415.272247
PSA89.79000
LogP1.98
Vapour Pressure0.0±1.9 mmHg at 25°C
Index of Refraction1.591

Synonyms

4-Androstene-3,17-dione-19-ol
15R-bimatoprost
19-hydroxyandrostenedione
4-androsten-19-ol-3,17-dione
(5E)-7-{(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-penten-1-yl]cyclopentyl}-N-ethyl-5-heptenamide
(5E)-7-{(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenylpent-1-en-1-yl]cyclopentyl}-N-ethylhept-5-enamide
19-Hydroxyandrostendione
5-Heptenamide, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-penten-1-yl]cyclopentyl]-N-ethyl-, (5E)-
19-Hydroxy-androst-4-en-3,17-dion
15-epi-bimatoprost
19-Hydroxy-4-androstene-3,17-dione
5-trans bimatoprost
CAS 1163135-92-9|(15R)-Bimatoprost
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