CAS 543-18-0|Guanidinoethyl sulfonate

Introduction:Basic information about CAS 543-18-0|Guanidinoethyl sulfonate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameGuanidinoethyl sulfonate
CAS Number543-18-0Molecular Weight167.18700
Density1.73g/cm3Boiling Point/
Molecular FormulaC3H9N3O3SMelting Point263-265ºC
MSDS/Flash Point/

Names

Nametaurocyamine
SynonymMore Synonyms

Guanidinoethyl sulfonate BiologicalActivity

DescriptionGuanidinoethyl sulfonate (Taurocyamine), a transport antagonist of taurine, induces much urinary taurine excretion with a resulting decrease in the tissue taurine content and readily produces taurine-deficient fetal rats in pregnant rats[1]. Guanidinoethyl sulfonate, a structural analogue of taurine, acts as a competitive inhibitor of taurine transport[2].
Related CatalogSignaling Pathways >>Others >>OthersResearch Areas >>Metabolic Disease
Target

Human Endogenous Metabolite

References

[1]. K Ejiri, et al. Effect of guanidinoethyl sulfonate on taurine concentrations and fetal growth in pregnant rats. Biol Neonate. 1987;51(4):234-40.

[2]. Luz M Suárez, et al.  The taurine transporter substrate guanidinoethyl sulfonate mimics the action of taurine on long-term synaptic potentiation. Amino Acids. 2016 Nov;48(11):2647-2656.

Chemical & Physical Properties

Density1.73g/cm3
Melting Point263-265ºC
Molecular FormulaC3H9N3O3S
Molecular Weight167.18700
Exact Mass167.03600
PSA124.65000
LogP0.62900
Index of Refraction1.618
InChIKeyJKLRIMRKZBSSED-UHFFFAOYSA-N
SMILESNC(N)=NCCS(=O)(=O)O

Safety Information

Risk Phrases34
Safety PhrasesS26-S36-S37-S39
RIDADRUN 3261
HS Code2925290090

Customs

HS Code2925290090
Summary2925290090 other imines and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

Synonyms

Guanidinoethyl Sulfonate
2-(diaminomethylideneamino)ethanesulfonic acid
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