CAS 112897-99-1|5′-O-[Bis(4-methoxyphenyl)phenylmethyl]cytidine

Introduction:Basic information about CAS 112897-99-1|5′-O-[Bis(4-methoxyphenyl)phenylmethyl]cytidine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Name5′-O-[Bis(4-methoxyphenyl)phenylmethyl]cytidine
CAS Number112897-99-1Molecular Weight545.58
Density1.34Boiling Point742.535ºC at 760 mmHg
Molecular FormulaC30H31N3O7Melting Point/
MSDS/Flash Point/

Names

Name5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
SynonymMore Synonyms

BiologicalActivity

Description5′-O-[Bis(4-methoxyphenyl)phenylmethyl]cytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related CatalogResearch Areas >>CancerSignaling Pathways >>Cell Cycle/DNA Damage >>Nucleoside Antimetabolite/Analog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

Chemical & Physical Properties

Density1.34
Boiling Point742.535ºC at 760 mmHg
Molecular FormulaC30H31N3O7
Molecular Weight545.58
Exact Mass545.21600
PSA139.28000
LogP2.81300
InChIKeySUENBDLQORXVMC-YULOIDQLSA-N
SMILESCOc1ccc(C(OCC2OC(n3ccc(N)nc3=O)C(O)C2O)(c2ccccc2)c2ccc(OC)cc2)cc1

Synonyms

5'-O-(4,4'-dimethoxytrityl)-cytidine
Uridine,5'-O-[bis(4-methoxyphenyl)phenylmethyl]-3-methyl
5'-O-(4,4'-dimethoxytrityl)-3-methyluridine
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