Introduction：Basic information about CAS 1217222-76-8|Furazolidone-D4, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Furazolidone-D4 |
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| CAS Number | 1217222-76-8 | Molecular Weight | 229.18 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C8H3D4N3O5 | Melting Point | / |
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| MSDS | ChineseUSA | Flash Point | / |
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| Symbol |
GHS08 | Signal Word | Warning |
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Names
| Name | 4,4,5,5-tetradeuterio-3-[(E)-(5-nitrofuran-2-yl)methylideneamino]-1,3-oxazolidin-2-one |
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| Synonym | More Synonyms |
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Furazolidone-D4 BiologicalActivity
| Description | Furazolidone-d4 is deuterium labeled Furazolidone. |
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| Related Catalog | Signaling Pathways >>Apoptosis >>ApoptosisResearch Areas >>InfectionSignaling Pathways >>Anti-infection >>Bacterial |
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| In Vitro | Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. |
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| References | [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Jiang X, et al. A novel application of furazolidone: anti-leukemic activity in acute myeloid leukemia. PLoS One. 2013 Aug 9;8(8):e72335. |
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Chemical & Physical Properties
| Molecular Formula | C8H3D4N3O5 |
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| Molecular Weight | 229.18 |
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| Exact Mass | 229.06400 |
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| PSA | 100.86000 |
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| LogP | 1.43500 |
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| InChIKey | PLHJDBGFXBMTGZ-QIBFQDEWSA-N |
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| SMILES | O=C1OCCN1N=Cc1ccc([N+](=O)[O-])o1 |
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Safety Information
| Symbol |
GHS08 |
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| Signal Word | Warning |
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| Hazard Statements | H361 |
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| Precautionary Statements | P281 |
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| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
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| Hazard Codes | Xn |
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| Risk Phrases | 62 |
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| Safety Phrases | 36/37 |
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| RIDADR | NONH for all modes of transport |
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Synonyms
| Furaxon-d4 |
| Furazolidon-d4 |
| Tikofuran-d4 |
| Diafuron-d4 |
| Giardil-d4 |
| Furazolidone-d4 |
| Trifurox-d4 |
| Topazone-d4 |
| Roptazol-d4 |
| Furazol-d4 |
