Introduction：Basic information about CAS 21888-98-2|benzetimide, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | benzetimide |
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| CAS Number | 21888-98-2 | Molecular Weight | 398.92600 |
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| Density | 1.178g/cm3 | Boiling Point | 543.9ºC at 760 mmHg |
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| Molecular Formula | C23H26N2O2 | Melting Point | 181-183° |
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| MSDS | / | Flash Point | 282.7ºC |
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Names
| Name | benzetimide |
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| Synonym | More Synonyms |
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benzetimide BiologicalActivity
| Description | Dexetimide ((+)-Benzetimide) is a high-affinity muscarinic receptor antagonist and a potent and persistent anticholinergic agent used to treat neuroleptic-induced parkinsonism[1]. |
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| Related Catalog | Signaling Pathways >>Neuronal Signaling >>mAChRResearch Areas >>Cardiovascular DiseaseSignaling Pathways >>GPCR/G Protein >>mAChR |
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| References | [1]. Speck AL, et al. The absolute configuration and crystal structure of the anticholinergic drug dexbenzetimide. Nature. 1971 Aug 20;232(5312):575-6. [2]. Müller-Gärtner HW, et al. Imaging muscarinic cholinergic receptors in human brain in vivo with Spect, [123I]4-iododexetimide, and [123I]4-iodolevetimide. J Cereb Blood Flow Metab. 1992 Jul;12(4):562-70. |
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Chemical & Physical Properties
| Density | 1.178g/cm3 |
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| Boiling Point | 543.9ºC at 760 mmHg |
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| Melting Point | 181-183° |
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| Molecular Formula | C23H26N2O2 |
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| Molecular Weight | 398.92600 |
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| Flash Point | 282.7ºC |
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| Exact Mass | 398.17600 |
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| PSA | 49.41000 |
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| LogP | 4.34190 |
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| Vapour Pressure | 6.86E-12mmHg at 25°C |
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| Index of Refraction | 1.597 |
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| InChIKey | LQQIVYSCPWCSSD-HSZRJFAPSA-N |
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| SMILES | O=C1CCC(c2ccccc2)(C2CCN(Cc3ccccc3)CC2)C(=O)N1 |
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Safety Information
| RIDADR | UN 3249 |
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| Packaging Group | III |
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| Hazard Class | 6.1(b) |
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Synonyms
| Dexbenzetimide |
| DEXETIMIDE HCL |
| Dexbenzetimid |
| Dextrobenzetimide |
