CAS 70155-54-3|Taurine-13C2

Introduction:Basic information about CAS 70155-54-3|Taurine-13C2, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameTaurine-13C2
CAS Number70155-54-3Molecular Weight127.13200
Density/Boiling Point/
Molecular FormulaC2H7NO3SMelting Point/
MSDSChineseUSAFlash Point/
Symbol
GHS07
Signal WordWarning

Names

Name2-aminoethanesulfonic acid
SynonymMore Synonyms

Taurine-13C2 BiologicalActivity

DescriptionTaurine-13C2 (2-Aminoethanesulfonic acid-13C2) is the 13C-labeled Taurine. Taurine, a sulphur-containing amino acid and an organic osmolyte involved in cell volume regulation, provides a substrate for the formation of bile salts, and plays a role in the modulation of intracellular free calcium concentration. Taurine has the ability to activate autophagy in adipocytes[1][2][3].
Related CatalogSignaling Pathways >>Autophagy >>AutophagyResearch Areas >>Metabolic Disease
In VitroStable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

[2]. Ripps H, Shen W. Review: taurine: a "very essential" amino acid. Mol Vis. 2012;18:2673-2686.

[3]. Xu YJ, et al. The potential health benefits of taurine in cardiovascular disease. Exp Clin Cardiol. 2008;13(2):57-65.

[4]. Kaneko H, et al. Taurine is an amino acid with the ability to activate autophagy in adipocytes. Amino Acids. 2018;50(5):527-535.

Chemical & Physical Properties

Molecular FormulaC2H7NO3S
Molecular Weight127.13200
Exact Mass127.02100
PSA88.77000
LogP0.61400
InChIKeyXOAAWQZATWQOTB-ZDOIIHCHSA-N
SMILESNCCS(=O)(=O)O

Safety Information

Symbol
GHS07
Signal WordWarning
Hazard StatementsH315-H319-H335
Precautionary StatementsP261-P305 + P351 + P338
Personal Protective Equipmentdust mask type N95 (US);Eyeshields;Gloves
RIDADRNONH for all modes of transport
RTECSWX0175000

Synonyms

[13C2]-Taurine
2-Aminoethane-13C2-sulfonic acid
Taurine-13C2
2-Aminoethansulfonsaeure
2-amino-[1,2-13C]ethanesulfonic acid
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