CAS 75498-96-3|Cefminox sodium

Introduction：Basic information about CAS 75498-96-3|Cefminox sodium, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Cefminox sodium BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Customs
6. Synonyms

Common Name	Cefminox sodium
CAS Number	75498-96-3	Molecular Weight	541.557
Density	/	Boiling Point	/
Molecular Formula	C₁₆H₂₀N₇NaO₇S₃	Melting Point	/
MSDS	/	Flash Point	/

Names

Name	(6R-(6-α,7-α))-7-((((2-Amino-2-carboxyethyl)thio)acetyl)amino)-7-methoxy-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid monosodium salt
Synonym	More Synonyms

Cefminox sodium BiologicalActivity

Description	Cefminox sodium (MT-141) is a semisynthetic cephamycin, which exhibits a broad spectrum of antibacterial activity[1]. Cefminox sodium (MT-141) also acts as a dual agonist of prostacyclin receptor (IP) and PPARγ, upregulates cAMP production and PTEN expression and inhibits Akt/mTOR signaling. Cefminox sodium (MT-141) also prevents pulmonary arterial hypertension[2].
Related Catalog	Research Areas >>Cardiovascular DiseaseResearch Areas >>InfectionSignaling Pathways >>GPCR/G Protein >>Prostaglandin ReceptorSignaling Pathways >>Cell Cycle/DNA Damage >>PPARSignaling Pathways >>Anti-infection >>Bacterial
Target	PPARγ IP Receptor Bacterial
References	[1]. Inouye S, et al. In vitro and in vivo antibacterial activities of MT-141, a new semisynthetic cephamycin, compared with those of five cephalosporins. Antimicrob Agents Chemother. 1984 Nov;26(5):722-9. [2]. Xia J, et al. Cefminox, a Dual Agonist of Prostacyclin Receptor and Peroxisome Proliferator-Activated Receptor-Gamma Identified by Virtual Screening, Has Therapeutic Efficacy against Hypoxia-Induced Pulmonary Hypertension in Rats. Front Pharmacol. 2018 Feb 23;9:134.

Chemical & Physical Properties

Molecular Formula	C₁₆H₂₀N₇NaO₇S₃
Molecular Weight	541.557
Exact Mass	541.048401
PSA	281.59000
InChIKey	SBIDXLKJYJVQOE-YNJMIPHHSA-M
SMILES	COC1(NC(=O)CSCC(N)C(=O)[O-])C(=O)N2C(C(=O)[O-])=C(CSc3nnnn3C)CSC21.[H+].[Na+]

Safety Information

HS Code	3003201900

Customs

HS Code	3003201900

Synonyms

Sodium (6R,7S)-7-({[(2-amino-2-carboxyethyl)sulfanyl]acetyl}amino)-7-methoxy-3-{[(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

CefMinox SodiuM Salt Heptahydrate

Meicelin Heptahydrate

CefMinox SodiuM Heptahydrate

Cefminox sodium

5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[2-[(2-amino-2-carboxyethyl)thio]acetyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-, sodium salt, (6R,7S)- (1:1)

Cefminox Sodium Salt

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