Introduction：Basic information about CAS 115404-57-4|niloticin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | niloticin |
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| CAS Number | 115404-57-4 | Molecular Weight | 456.70 |
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| Density | 1.1±0.1 g/cm3 | Boiling Point | 538.5±45.0 °C at 760 mmHg |
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| Molecular Formula | C30H48O3 | Melting Point | / |
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| MSDS | / | Flash Point | 165.4±22.2 °C |
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Names
| Name | Niloticin |
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| Synonym | More Synonyms |
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niloticin BiologicalActivity
| Description | Niloticin, tetracyclic triterpenoid compound, is a osteoclastogenesis inhibitor. Niloticin shows anti-viral, antioxidative, and mosquitocidal activities. Niloticin inhibits osteoclastogenesis by blocking RANKL-RANK interaction and suppressing the AKT, MAPK, and NF-κB signaling pathways[1]. |
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| Related Catalog | Research Areas >>InfectionSignaling Pathways >>PI3K/Akt/mTOR >>Akt |
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| References | [1]. Xu H, et al. Niloticin inhibits osteoclastogenesis by blocking RANKL-RANK interaction and suppressing the AKT, MAPK, and NF-κB signaling pathways. Biomed Pharmacother. 2022 May;149:112902. |
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Chemical & Physical Properties
| Density | 1.1±0.1 g/cm3 |
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| Boiling Point | 538.5±45.0 °C at 760 mmHg |
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| Molecular Formula | C30H48O3 |
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| Molecular Weight | 456.70 |
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| Flash Point | 165.4±22.2 °C |
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| Exact Mass | 456.360352 |
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| PSA | 49.83000 |
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| LogP | 7.24 |
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| Vapour Pressure | 0.0±3.2 mmHg at 25°C |
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| Index of Refraction | 1.543 |
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| InChIKey | GKQMMZUXYRXFOH-UHFFFAOYSA-N |
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| SMILES | CC(CC(O)C1OC1(C)C)C1CCC2(C)C3=CCC4C(C)(C)C(=O)CCC4(C)C3CCC12C |
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Safety Information
Synonyms
| niloticin |
| (13α,14β,17α,20S,23R,24S)-23-Hydroxy-24,25-epoxylanost-7-en-3-one |
| Lanost-7-en-3-one, 24,25-epoxy-23-hydroxy-, (13α,14β,17α,20S,23R,24S)- |
