CAS 21150-23-2|γ-Amanitin
Introduction：Basic information about CAS 21150-23-2|γ-Amanitin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | γ-Amanitin | ||
|---|---|---|---|
| CAS Number | 21150-23-2 | Molecular Weight | 902.970 |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 1566.5±65.0 °C at 760 mmHg |
| Molecular Formula | C39H54N10O13S | Melting Point | / |
| MSDS | / | Flash Point | 901.2±34.3 °C |
Names
| Name | 2-[34-sec-Butyl-8,22-dihydroxy-13-(3-hydroxy-2-butanyl)-27-oxido-2,5,11,14,30,33,36,39-octaoxo-27-thia-3,6,12,15,25,29,32,35,38-nonaazapentacyclo[14.12.11.06,10.018,26.019,24]nonatriaconta-18(26),19,21,23-tetraen-4-yl]acetamide |
|---|---|
| Synonym | More Synonyms |
γ-Amanitin BiologicalActivity
| Description | γ-Amanitin an ADC cytotoxin and isolated from the mushroom. γ-Amanitin inhibits RNA polymerase II and disrupts synthesis of mRNA. γ-Amanitin shows similar effects to α-Amanitin (HY-19610) and β-Amanitin (HY-125586)[1]. |
|---|---|
| Related Catalog | Research Areas >>CancerSignaling Pathways >>Cell Cycle/DNA Damage >>DNA/RNA SynthesisSignaling Pathways >>Antibody-drug Conjugate >>ADC Cytotoxin |
| Target | Traditional Cytotoxic Agents |
| References | [1]. Gamma-Amanitin |
Chemical & Physical Properties
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Boiling Point | 1566.5±65.0 °C at 760 mmHg |
| Molecular Formula | C39H54N10O13S |
| Molecular Weight | 902.970 |
| Flash Point | 901.2±34.3 °C |
| Exact Mass | 902.359253 |
| PSA | 405.28000 |
| LogP | -7.98 |
| Vapour Pressure | 0.0±0.3 mmHg at 25°C |
| Index of Refraction | 1.684 |
| InChIKey | WVHGJJRMKGDTEC-WUQNCEDYSA-N |
| SMILES | CCC(C)C1NC(=O)CNC(=O)C2Cc3c([nH]c4cc(O)ccc34)S(=O)CC(NC(=O)CNC1=O)C(=O)NC(CC(N)=O)C(=O)N1CC(O)CC1C(=O)NC(C(C)C(C)O)C(=O)N2 |
Safety Information
| RIDADR | UN 1544 6.1/PG 1 |
|---|
Synonyms
| 2-[34-sec-Butyl-8,22-dihydroxy-13-(3-hydroxy-2-butanyl)-27-oxido-2,5,11,14,30,33,36,39-octaoxo-27-thia-3,6,12,15,25,29,32,35,38-nonaazapentacyclo[14.12.11.0.0.0]nonatriaconta-18(26 ),19,21,23-tetraen-4-yl]acetamide |
| 9,18-(Iminoethanoiminoethanoiminoethanoiminomethano)pyrrolo[1',2':8,9][1,5,8,11,14]thiatetraazacyclooctadecino[18,17-b]indole-6-acetamide, 1,2,3,5,6,7,8,9,10,12,17,18,19,20,21,22,23,23a-octadecahydro-2,14-dihydroxy-21-(2-hydroxy-1-methylpropyl)-29-(1-methylpropyl)-5,8,20,23,24,27,30,33-octaoxo-, 11-oxide |
