Introduction：Basic information about CAS 57944-13-5|3'-Deoxy-3'-fluorouridine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 3'-Deoxy-3'-fluorouridine |
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| CAS Number | 57944-13-5 | Molecular Weight | 246.19 |
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| Density | 1.6±0.1 g/cm3 | Boiling Point | / |
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| Molecular Formula | C9H11FN2O5 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | 1-[(2R,3S,4S,5R)-4-fluoro-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione |
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| Synonym | More Synonyms |
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3'-Deoxy-3'-fluorouridine BiologicalActivity
| Description | 3′-Deoxy-3′-fluorouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. |
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| Related Catalog | Signaling Pathways >>Cell Cycle/DNA Damage >>Nucleoside Antimetabolite/AnalogResearch Areas >>Others |
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| References | [1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. |
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Chemical & Physical Properties
| Density | 1.6±0.1 g/cm3 |
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| Molecular Formula | C9H11FN2O5 |
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| Molecular Weight | 246.19 |
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| Exact Mass | 246.065201 |
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| PSA | 104.81000 |
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| LogP | -1.18 |
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| Index of Refraction | 1.608 |
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| InChIKey | FVBOTRDLABQYMI-XVFCMESISA-N |
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| SMILES | O=c1ccn(C2OC(CO)C(F)C2O)c(=O)[nH]1 |
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Synonyms
| 1-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)uracil |
| 3'-Deoxy-3'-fluorouridine |
| 3'-Fluoro-3'-deoxyuridine |
| Uridine,3'-deoxy-3'-fluoro |
| Uridine, 3'-deoxy-3'-fluoro- |
