Introduction：Basic information about CAS 110026-03-4|taurohyodeoxycholic acid sodium salt, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | taurohyodeoxycholic acid sodium salt |
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| CAS Number | 110026-03-4 | Molecular Weight | 540.71 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C26H47NNaO7S+ | Melting Point | 168ºC (dec.)(lit.) |
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| MSDS | ChineseUSA | Flash Point | / |
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Names
| Name | taurohyodeoxycholic acid sodium salt |
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| Synonym | More Synonyms |
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taurohyodeoxycholic acid sodium salt BiologicalActivity
| Description | Taurodeoxychloic Acid (sodium hydrate) prevents apoptosis by blocking a calcium-mediated apoptotic pathway as well as caspase-12 activation. Taurodeoxychloic Acid (sodium hydrate) is investigated for use in several conditions such as Primary Biliary Cirrhosis (PBC), insulin resistance, amyloidosis, Cystic Fibrosis, Cholestasis, and Amyotrophic Lateral Sclerosis[1]. |
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| Related Catalog | Signaling Pathways >>Apoptosis >>ApoptosisSignaling Pathways >>Apoptosis >>CaspaseResearch Areas >>Inflammation/ImmunologyResearch Areas >>Metabolic Disease |
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| Target | Caspase-12 |
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| In Vivo | Taurodeoxychloic Acid (TUDCA) is neuroprotective in a transgenic animal model of Huntington’s disease[2]. |
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| References | [1]. Xie Q, et al. Effect of tauroursodeoxycholic acid on endoplasmic reticulum stress-induced caspase-12 activation. Hepatology. 2002 Sep;36(3):592-601. [2]. Keene CD, et al. Tauroursodeoxycholic acid, a bile acid, is neuroprotective in a transgenic animal model of Huntington's disease. Proc Natl Acad Sci U S A. 2002 Aug 6;99(16):10671-6. |
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Chemical & Physical Properties
| Melting Point | 168ºC (dec.)(lit.) |
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| Molecular Formula | C26H47NNaO7S+ |
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| Molecular Weight | 540.71 |
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| Exact Mass | 521.278687 |
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| PSA | 135.14000 |
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| LogP | 4.52640 |
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| Storage condition | 2-8℃ |
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Safety Information
| Hazard Codes | Xn: Harmful; |
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| Risk Phrases | 22-37 |
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| Safety Phrases | 22-36 |
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| WGK Germany | 3 |
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Synonyms
| SODIUM TAUROHYODEOXYCHOLATE |
| Sodium taurohyodeoxycholate hydrate |
| Sodium 2-{[(3α,5β,6α)-3,6-dihydroxy-24-oxocholan-24-yl]amino}ethanesulfonate |
| Ethanesulfonic acid, 2-[[(3α,5β,6α)-3,6-dihydroxy-24-oxocholan-24-yl]amino]-, sodium salt (1:1) |
| taurohyodeoxycholic acid sodium hydrate |
