CAS 579-75-9|2-Methoxybenzoic acid
Introduction：Basic information about CAS 579-75-9|2-Methoxybenzoic acid, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 2-Methoxybenzoic acid | ||
|---|---|---|---|
| CAS Number | 579-75-9 | Molecular Weight | 152.147 |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 279.9±13.0 °C at 760 mmHg |
| Molecular Formula | C8H8O3 | Melting Point | 98-100 °C(lit.) |
| MSDS | USA | Flash Point | 116.3±13.3 °C |
Names
| Name | O-methylsalicylic acid |
|---|---|
| Synonym | More Synonyms |
2-Methoxybenzoic acid BiologicalActivity
| Description | 2-Methoxybenzoic acid is used as an internal standard of salicylic acid and its putative biosynthetic precursors in cucumber leaves. Another known use is in the synthesis of Benextramine. |
|---|---|
| Related Catalog | Natural Products >>Acids and AldehydesResearch Areas >>Cancer |
| Target | Human Endogenous Metabolite |
| References | [1]. Meuwly P, et al. Ortho-anisic acid as internal standard for the simultaneous quantitation of salicylic acid and its putative biosynthetic precursors in cucumber leaves. Anal Biochem. 1993 Nov 1;214(2):500-5. |
Chemical & Physical Properties
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 279.9±13.0 °C at 760 mmHg |
| Melting Point | 98-100 °C(lit.) |
| Molecular Formula | C8H8O3 |
| Molecular Weight | 152.147 |
| Flash Point | 116.3±13.3 °C |
| Exact Mass | 152.047348 |
| PSA | 46.53000 |
| LogP | 1.50 |
| Vapour Pressure | 0.0±0.6 mmHg at 25°C |
| Index of Refraction | 1.546 |
| InChIKey | ILUJQPXNXACGAN-UHFFFAOYSA-N |
| SMILES | COc1ccccc1C(=O)O |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 3 gm/kg
- TOXIC EFFECTS :
- Behavioral - excitement Behavioral - muscle contraction or spasticity
- REFERENCE :
- BSRSA6 Bulletin de la Societe Royale des Sciences de Liege. (Societe Royale des Sciences de Liege, Universite de Liege, 15, Ave des Tilleuls, B-4000 Liege, Belgium) V.1- 1932- Volume(issue)/page/year: 47,202,1978
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2750 mg/kg
- TOXIC EFFECTS :
- Behavioral - excitement Behavioral - muscle contraction or spasticity
- REFERENCE :
- BSRSA6 Bulletin de la Societe Royale des Sciences de Liege. (Societe Royale des Sciences de Liege, Universite de Liege, 15, Ave des Tilleuls, B-4000 Liege, Belgium) V.1- 1932- Volume(issue)/page/year: 47,202,1978
- TYPE OF TEST :
- LD - Lethal dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CBCCT* "Summary Tables of Biological Tests," National Research Council Chemical-Biological Coordination Center. (National Academy of Science Library, 2101 Constitution Ave., NW, Washington, DC 20418) Volume(issue)/page/year: 6,52,1954
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 300 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CKFRAY Ceskoslovenska Farmacie. (PNS-Ustredni Expedice a Dovoz Tisku, Kafkova 19, 160 00 Prague 6, Czechoslovakia) V.1- 1952- Volume(issue)/page/year: 31,236,1982
Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Hazard Codes | Xi |
| Risk Phrases | R36/37/38 |
| Safety Phrases | S24/25 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| RTECS | BZ4385000 |
| HS Code | 2918990090 |
Customs
| HS Code | 2918990090 |
|---|---|
| Summary | 2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
Articles14
More Articles| Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk). J. Med. Chem. 48 , 3269-79, (2005) Growing interest in the use of both the logarithm of the partition coefficient of the neutral species in the alkane/water system (log P(N)(alk)) and the difference between log P(N)(oct) (the logarithm... | |
| Endogenous salicylic acid accumulation is required for chilling tolerance in cucumber (Cucumis sativus L.) seedlings. Planta 240(4) , 687-700, (2014) Salicylic acid (SA) is an important plant hormone, and its exogenous application can induce tolerance to multiple environmental stresses in plants. In this study, we examine the potential involvement ... | |
| Purification and properties of gentisate 1,2-dioxygenase from Moraxella osloensis. J. Bacteriol. 121(3) , 794-9, (1975) Gentisate:oxygen 1,2-oxidoreductase (decyclizing) (EC 1.13.11.4; gentisate 1,2-dioxygenase) from Moraxella osloensis was purified to homogeneity as shown by polyacrylamide gel electrophoresis. The enz... |
Synonyms
| 2-OMeC6H4COOH |
| 2-methoxybenzoic |
| 2-CARBOXYANISOLE |
| RARECHEM AL BO 0025 |
| 2-Anisic acid |
| EINECS 209-447-8 |
| o-Anisic Acid |
| o-Anisc Acid |
| Methylsalicylic acid |
| O-METHYLSALICYLIC ACID |
| o-anisic |
| methoxybenzoic acid |
| 2-Methoxy-benzoic acid |
| 2-Methoxybenzoic acid |
| ortho-methoxybenzoic acid |
| Benzoic acid, 2-methoxy- |
| O-METHOXYBENZOIC ACID |
| ortho-anisic acid |
| MFCD00002431 |
