Introduction：Basic information about CAS 1445-69-8|2,3-Dihydrophthalazine-1,4-dione, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 2,3-Dihydrophthalazine-1,4-dione |
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| CAS Number | 1445-69-8 | Molecular Weight | 162.145 |
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| Density | 1.3±0.1 g/cm3 | Boiling Point | 523.5ºC at 760 mmHg |
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| Molecular Formula | C8H6N2O2 | Melting Point | >300 °C(lit.) |
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| MSDS | ChineseUSA | Flash Point | 270.4ºC |
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Names
| Name | Phthalhydrazide |
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| Synonym | More Synonyms |
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Chemical & Physical Properties
| Density | 1.3±0.1 g/cm3 |
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| Boiling Point | 523.5ºC at 760 mmHg |
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| Melting Point | >300 °C(lit.) |
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| Molecular Formula | C8H6N2O2 |
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| Molecular Weight | 162.145 |
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| Flash Point | 270.4ºC |
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| Exact Mass | 162.042923 |
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| PSA | 65.72000 |
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| LogP | 0.57 |
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| Vapour Pressure | 1.41E-11mmHg at 25°C |
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| Index of Refraction | 1.587 |
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| InChIKey | KGLPWQKSKUVKMJ-UHFFFAOYSA-N |
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| SMILES | O=c1[nH][nH]c(=O)c2ccccc12 |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- TH8890080
- CHEMICAL NAME :
- 1,4-Phthalazinedione, 2,3-dihydro-
- CAS REGISTRY NUMBER :
- 1445-69-8
- LAST UPDATED :
- 199509
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C8-H6-N2-O2
- MOLECULAR WEIGHT :
- 162.16
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 700 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARPMAS Archiv der Pharmazie (Weinheim, Germany) (VCH Pub., Inc., 303 NW 12th Ave., Deerfield Beach, FL 33441) V.51-261, 1835-1923; V.305- 1972- Volume(issue)/page/year: 327,237,1994 ** REPRODUCTIVE DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- DOSE :
- 700 mg/kg
- SEX/DURATION :
- female 7 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Fertility - female fertility index (e.g. # females pregnant per # sperm positive females; # females pregnant per # females mated)
- REFERENCE :
- ARPMAS Archiv der Pharmazie (Weinheim, Germany) (VCH Pub., Inc., 303 NW 12th Ave., Deerfield Beach, FL 33441) V.51-261, 1835-1923; V.305- 1972- Volume(issue)/page/year: 327,237,1994
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Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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| Safety Phrases | S24/25 |
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| RIDADR | NONH for all modes of transport |
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| WGK Germany | 3 |
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| RTECS | TH8890080 |
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| HS Code | 2933990090 |
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Customs
| HS Code | 2933990090 |
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| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Articles5
More Articles
| Effects of 2,3-dihydrophthalazine-1,4-dione on Sprague Dawley rats lipid metabolism and serum lipoproteins. Biomed. Biochim. Acta 47(4-5) , 423-33, (1988) 2,3-Dihydrophthalazine-1,4-dione effectively lowers serum levels of cholesterol and triglycerides in Sprague Dawley rats after two weeks, after which the cholesterol levels continued to decline. The m... | |
| Anti-inflammatory activity of 2,3-dihydrophthalazine-1,4-diones in CF1 mice. Int. J. Tissue React. 18(2-3) , 47-55, (1996) 2,3-Dihydrophthalazine-1,4-diones were observed to be potent anti-inflammatory agents as well as capable of protecting against endotoxin shock in mice at 8 mg/kg i.p. These agents blocked both locally... | |
| The anti-neoplastic activity of 2,3-dihydrophthalazine-1,4-dione and N-butyl-2,3-dihydrophthalazine-1,4-dione in human and murine tumor cells. Anticancer Drugs 3(1) , 55-62, (1992) 2,3-Dihydrophthalazine-1,4-dione derivatives demonstrated potent cytotoxicity against the growth of murine leukemia cells and human single cell suspension, i.e. Tmolt3 leukemia and HeLa-S3, as well as... | |
Synonyms
| 1,4-Phthalazinedione |
| 1,4-DIHYDROXYPHTHALAZINE |
| Phthalohydrazide |
| N,N'-Phthaloylhydrazine |
| 2,3-DIHYDRO-PHTHALAZINE-1,4-DIONE |
| 1,4-phthalazinediol |
| 2,3-dihydrophthalazine-1,4-dione |
| 2,3-Dihydro-1,4-phthalazinedione |
| Phthalhydrizide |
| PHTHALHYDRAZINE |
| PHTHALIC HYDRAZIDE |
| PHTALYLHYDRAZINE |
| phthalazine-1,4-diol |
| Phthalodihydrazide |
| 1,4-Phthalazinedione, 2,3-dihydro- |
| 2,3-Dihydro-1,4-phthalazinedione ; Phthalhydrazine |
| EINECS 215-893-4 |
| MFCD00006888 |
| 1,4-Ketophthalazine |
| Phthaloylhydrazine |
