CAS 51166-71-3|Heptakis(2,6-di-O-methyl)-b-cyclodextrin

Introduction：Basic information about CAS 51166-71-3|Heptakis(2,6-di-O-methyl)-b-cyclodextrin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Heptakis(2,6-di-O-methyl)-b-cyclodextrin BiologicalActivity
3. Chemical & Physical Properties
4. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
5. Safety Information
6. Articles25
7. Synonyms

Common Name	Heptakis(2,6-di-O-methyl)-b-cyclodextrin
CAS Number	51166-71-3	Molecular Weight	1331.356
Density	1.4±0.1 g/cm3	Boiling Point	1203.6±65.0 °C at 760 mmHg
Molecular Formula	C₅₆H₉₈O₃₅	Melting Point	298 - 310ºC
MSDS	ChineseUSA	Flash Point	681.7±34.3 °C

Names

Name	2,6-di-o-methyl-beta-cyclodextrin
Synonym	More Synonyms

Heptakis(2,6-di-O-methyl)-b-cyclodextrin BiologicalActivity

Description	2,6-Di-O-methyl-β-cyclodextrin is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Related Catalog	Research Areas >>Others

Chemical & Physical Properties

Density	1.4±0.1 g/cm3
Boiling Point	1203.6±65.0 °C at 760 mmHg
Melting Point	298 - 310ºC
Molecular Formula	C₅₆H₉₈O₃₅
Molecular Weight	1331.356
Flash Point	681.7±34.3 °C
Exact Mass	1330.588867
PSA	400.05000
LogP	6.96
Vapour Pressure	0.0±0.6 mmHg at 25°C
Index of Refraction	1.553
InChIKey	QGKBSGBYSPTPKJ-UZMKXNTCSA-N
SMILES	COCC1OC2OC3C(COC)OC(OC4C(COC)OC(OC5C(COC)OC(OC6C(COC)OC(OC7C(COC)OC(OC8C(COC)OC(OC1C(O)C2OC)C(OC)C8O)C(OC)C7O)C(OC)C6O)C(OC)C5O)C(OC)C4O)C(OC)C3O
Storage condition	Refrigerator
Water Solubility	H2O: soluble

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: GU2293500

CHEMICAL NAME :: beta-Cyclodextrin, 2(sup A),2(sup B),2(sup C),2(sup D),2(sup E),2(sup F),2(sup G),6(sup A),6 (sup B),6(sup C),6(sup D),6(sup E),6(sup F),6(sup G)-tetradeca-O-methyl-

CAS REGISTRY NUMBER :: 51166-71-3

LAST UPDATED :: 199406

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C56-H98-O35

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 350 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JOIPDF Journal of Inclusion Phenomena. (D. Reidel Publishing Co., c/o Kluwer Academic Publishers, P.O. Box 322, 3300 AH Dordrecht, Netherlands) V.1- 1983- Volume(issue)/page/year: 1,135,1983

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 220 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JOIPDF Journal of Inclusion Phenomena. (D. Reidel Publishing Co., c/o Kluwer Academic Publishers, P.O. Box 322, 3300 AH Dordrecht, Netherlands) V.1- 1983- Volume(issue)/page/year: 1,135,1983

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >3 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JOIPDF Journal of Inclusion Phenomena. (D. Reidel Publishing Co., c/o Kluwer Academic Publishers, P.O. Box 322, 3300 AH Dordrecht, Netherlands) V.1- 1983- Volume(issue)/page/year: 1,135,1983

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >150 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JOIPDF Journal of Inclusion Phenomena. (D. Reidel Publishing Co., c/o Kluwer Academic Publishers, P.O. Box 322, 3300 AH Dordrecht, Netherlands) V.1- 1983- Volume(issue)/page/year: 1,135,1983

Safety Information

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Safety Phrases	24/25
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	GU2293500
HS Code	29400090

Articles25

Evaluation of the separation mechanism of electrokinetic chromatography with a microemulsion and cyclodextrins using NMR and molecular modeling.

Electrophoresis 32(21) , 3062-9, (2011)

Electrokinetic chromatography (EKC) allows the separation of closely related substances by the detection of fine effects in analyte-separation system interactions. With the goal of understanding the f...

Synthesis, cytotoxicity, and phase-solubility study of cyclodextrin click clusters.

J. Pharm. Sci. 103(10) , 3183-9, (2014)

To explore the possibility of cyclodextrin click clusters (CCCs) as a new cyclodextrin-based excipient, we prepared three different CCCs; heptakis{6-(4-hydroxymethyl-1H-[1,2,3]triazol-1-yl)-6-deoxy}-β...

Host-guest interaction between new nitrooxoisoaporphine and β-cyclodextrins: synthesis, electrochemical, electron spin resonance and molecular modeling studies.

Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 102 , 226-34, (2013)

A new nitrooxoisoaporphine derivative was synthetized and characterized by cyclic voltammetry and electron spin resonance. Its aqueous solubility was improved by complexes formation with β-cyclodextri...

Synonyms

Dimethyl-beta-cyclodextrin,methylated beta-cyclodextrins

2,6-Di-O-methyl-β-cyclodextrin

Dimethyl β-cyclodextrin

Heptakis(2,6-di-O-methyl)-b-cyclodextrin

(1S,3R,5R,6S,8R,10R,11S,13R,15R,16S,18R,20R,21S,23R,25R,26S,28R,30R,31S,33R,35R,36S,37R,38S,39R,40S,41R,42S,43R,44S,45R,46S,47R,48S,49R)-37,39,41,43,45,47,49-Heptamethoxy-5,10,15,20,25,30,35-heptakis( ;methoxymethyl)-2,4,7,9,12,14,17,19,22,24,27,29,32,34-tetradecaoxaoctacyclo[31.2.2.2.2.2.2.2.2]nonatetracontane-36,38,40,42,44,46,48-heptol

MFCD00011616

(1S,3R,5R,6S,8R,10R,11S,13R,15R,16S,18R,20R,21S,23R,25R,26S,28R,30R,31S,33R,35R,36S,37R,38S,39R,40S,41R,42S,43R,44S,45R,46S,47R,48S,49R)-37,39,41,43,45,47,49-Heptamethoxy-5,10,15,20,25,30,35-heptakis(methoxymethyl)-2,4,7,9,12,14,17,19,22,24,27,29,32,34-tetradecaoxaoctacyclo[31.2.2.2.2.2.2.2.2]nonatetracontane-36,38,40,42,44,46,48-heptol (non-preferred name)

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