CAS 73-40-5|Guanine
Introduction：Basic information about CAS 73-40-5|Guanine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Guanine | ||
|---|---|---|---|
| CAS Number | 73-40-5 | Molecular Weight | 151.126 |
| Density | 2.2±0.1 g/cm3 | Boiling Point | 561.5±42.0 °C at 760 mmHg |
| Molecular Formula | C5H5N5O | Melting Point | >300 °C(lit.) |
| MSDS | ChineseUSA | Flash Point | 293.4±27.9 °C |
| Symbol | GHS07 | Signal Word | Warning |
Names
| Name | Guanine |
|---|---|
| Synonym | More Synonyms |
Guanine BiologicalActivity
| Description | Guanine is one of the fundamental components of nucleic acids (DNA and RNA). Guanine is a purine derivative, consisting of a fused pyrimidine-imidazole ring system with conjugated double bonds. |
|---|---|
| Related Catalog | Signaling Pathways >>Cell Cycle/DNA Damage >>DNA/RNA SynthesisResearch Areas >>Cancer |
Chemical & Physical Properties
| Density | 2.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 561.5±42.0 °C at 760 mmHg |
| Melting Point | >300 °C(lit.) |
| Molecular Formula | C5H5N5O |
| Molecular Weight | 151.126 |
| Flash Point | 293.4±27.9 °C |
| Exact Mass | 151.049408 |
| PSA | 100.45000 |
| LogP | -2.03 |
| Vapour Pressure | 0.0±1.6 mmHg at 25°C |
| Index of Refraction | 2.047 |
| Storage condition | 2-8°C |
| Stability | Stable. Incompatible with strong oxidizing agents. |
| Water Solubility | practically insoluble |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- LD - Lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >3333 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD - Lethal dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >1 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1300 mg/kg/26W-I
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Skin and Appendages - tumors Reproductive - Tumorigenic effects - ovarian tumors
MUTATION DATA - TEST SYSTEM :
- Rodent - mouse
- DOSE/DURATION :
- 15 mg/kg
- REFERENCE :
- NULSAK Nucleus (Calcutta). (Dr. A.K. Sharma, Centre of Advanced Studies in Cell and Chromosome Research, Calcutta, 35 Baliygunge Circular Rd., Calcutta 700 019, India) V.1- 1958- Volume(issue)/page/year: 19,40,1976 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X2576 No. of Facilities: 1778 (estimated) No. of Industries: 3 No. of Occupations: 3 No. of Employees: 4133 (estimated) No. of Female Employees: 3339 (estimated)
- TEST SYSTEM :
- Rodent - mouse
- DOSE/DURATION :
- 15 mg/kg
- REFERENCE :
- NULSAK Nucleus (Calcutta). (Dr. A.K. Sharma, Centre of Advanced Studies in Cell and Chromosome Research, Calcutta, 35 Baliygunge Circular Rd., Calcutta 700 019, India) V.1- 1958- Volume(issue)/page/year: 19,40,1976 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X2576 No. of Facilities: 1778 (estimated) No. of Industries: 3 No. of Occupations: 3 No. of Employees: 4133 (estimated) No. of Female Employees: 3339 (estimated)
Safety Information
| Symbol | GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi:Irritant |
| Risk Phrases | R36/37/38 |
| Safety Phrases | S26-S36-S37/39 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| RTECS | MF8260000 |
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Synonyms
| MFCD00071533 |
| dewpearl |
| Guanin |
| 2-amino-Hypoxanthine |
| 9H-purin-6-ol, 2-amino- |
| 2-amino-3,7-dihydro-6H-purin-6-one |
| 7H-Purin-6-ol, 2-amino- |
| Guanine |
| 2-amino-9H-purin-6-ol |
| Guanie |
| 2-amino-6-oxypurine |
| Gua |
| guamine |
| EINECS 200-799-8 |
| 2-amino-1,7-dihydro-6H-purin-6-one |
| 2-amino-1,9-dihydro-6H-purin-6-one |
| quanine |
| 2-amino-6-hydroxypurine |
| Ganciclovir Impurity 6 |
