CAS 84954-93-8|Rosarin

Introduction:Basic information about CAS 84954-93-8|Rosarin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameRosarin
CAS Number84954-93-8Molecular Weight428.430
Density1.5±0.1 g/cm3Boiling Point730.8±60.0 °C at 760 mmHg
Molecular FormulaC20H28O10Melting Point/
MSDSChineseUSAFlash Point395.8±32.9 °C

Names

NameRosavin
SynonymMore Synonyms

Rosarin BiologicalActivity

DescriptionRosarin is a cinnamyl alcohol glycoside isolated from Rhodiola rosea. Rosarin has anti-inflammatory and neuroprotective effects. Rosarin supresses the expression of the proinflammatory factors iNOS, IL-1 β, and TNF- α in the kidney and prefrontal cortex of brain in mice [1].
Related CatalogSignaling Pathways >>Others >>OthersResearch Areas >>Neurological Disease
In VitroRosarin (0-50 μg/ml; 18 hours) pretreats 30 mins in LPS-induced BV-2 cells supresses iNOS and cytokines expression in a concentration-dependent manner in the murine BV2 cells[1].
References

[1]. Lee Y, et al. Anti-Inflammatory and Neuroprotective Effects of Constituents Isolated from Rhodiola rosea.Evid Based Complement Alternat Med. 2013;2013:514049.

Chemical & Physical Properties

Density1.5±0.1 g/cm3
Boiling Point730.8±60.0 °C at 760 mmHg
Molecular FormulaC20H28O10
Molecular Weight428.430
Flash Point395.8±32.9 °C
Exact Mass428.168243
PSA158.30000
LogP2.03
Vapour Pressure0.0±2.5 mmHg at 25°C
Index of Refraction1.635
InChIKeyIEBFEMIXXHIISM-YZOUKVLTSA-N
SMILESOCC1OC(OCC2OC(OCC=Cc3ccccc3)C(O)C(O)C2O)C(O)C1O
Storage condition2-8°C

Safety Information

RIDADRNONH for all modes of transport

Synonyms

(2E)-3-Phenylprop-2-en-1-yl 6-O-α-L-arabinofuranosyl-β-D-glucopyranoside
MFCD04039808
(2E)-3-Phenyl-2-propen-1-yl 6-O-α-L-arabinofuranosyl-β-D-glucopyranoside
β-D-Glucopyranoside, (2E)-3-phenyl-2-propen-1-yl 6-O-α-L-arabinofuranosyl-
Rosarin
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