CAS 751-03-1|Obacunone
| Common Name | Obacunone | ||
|---|---|---|---|
| CAS Number | 751-03-1 | Molecular Weight | 454.512 |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 626.2±55.0 °C at 760 mmHg |
| Molecular Formula | C26H30O7 | Melting Point | / |
| MSDS | ChineseUSA | Flash Point | 332.5±31.5 °C |
Names
| Name | Obacunone |
|---|---|
| Synonym | More Synonyms |
Obacunone BiologicalActivity
| Description | Obacunone, isolated from seeds of Marsh White grapefruit, exhibits anti-tumor activity by the induction of apoptosis[1]. |
|---|---|
| Related Catalog | Signaling Pathways >>Apoptosis >>ApoptosisResearch Areas >>Cancer |
| References | [1]. Chidambara Murthy KN, et al. Obacunone and obacunone glucoside inhibit human colon cancer (SW480) cells by the induction of apoptosis. Food Chem Toxicol. 2011 Jul;49(7):1616-25. |
Chemical & Physical Properties
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 626.2±55.0 °C at 760 mmHg |
| Molecular Formula | C26H30O7 |
| Molecular Weight | 454.512 |
| Flash Point | 332.5±31.5 °C |
| Exact Mass | 454.199158 |
| PSA | 95.34000 |
| LogP | 2.91 |
| Vapour Pressure | 0.0±1.8 mmHg at 25°C |
| Index of Refraction | 1.592 |
| InChIKey | MAYJEFRPIKEYBL-OASIGRBWSA-N |
| SMILES | CC1(C)OC(=O)C=CC2(C)C1CC(=O)C1(C)C2CCC2(C)C(c3ccoc3)OC(=O)C3OC321 |
| Storage condition | 2~8℃ |
Safety Information
| Hazard Codes | Xi |
|---|---|
| Safety Phrases | 24/25 |
| RIDADR | NONH for all modes of transport |
| RTECS | RR1104200 |
Articles19
More Articles| [Simultaneous determination of jatrorrhizine, palmatine, berberine, and obacunone in Phellodendri Amurensis Cortex by RP-HPLC]. Zhongguo Zhong Yao Za Zhi 35(16) , 2061-4, (2010) To develop a HPLC method to determine the content of jatrorrhizine, palmatine, berberine, and obacunone in Phellodendri Amurensis Cortex simultaneously. MEHTOD: The separations were carried out at 25 ... | |
| Chemopreventive effect of a mixture of Chinese Herbs (antitumor B) on chemically induced oral carcinogenesis. Mol. Carcinog. 52(1) , 49-56, (2013) In this study, we evaluated chemopreventive efficacy of Antitumor B, a Chinese herbal mixture of six plants (Sophora tonkinensis, Polygonum bistorta, Prunella vulgaris, Sonchus arvensis L., Dictamnus ... | |
| Citrus limonoids obacunone and limonin inhibit azoxymethane-induced colon carcinogenesis in rats. Biofactors 13(1-4) , 213-8, (2000) Obacunone and limonin are bitter limonoids in citrus. Their modifying effects on the development of aberrant crypt foci (ACF), the activity of detoxification enzymes, glutathione S-transferase (GST) a... |
Synonyms
| (5aR,5bR,7aS,8S,10aS,11aR,11bR,13aR)-8-(3-Furyl)-1,1,5a,7a,11b-pentamethyl-5b,6,7,7a,8,11b,13,13a-octahydrooxireno[4,4a]isochromeno[6,5-g][2]benzoxepine-3,10,12(1H,5aH,10aH)-trione |
| OBACUNON |
| Tricoccin S3 |
| (5aR,5bR,7aS,8R,10aS,11aR,11bR,13aR)-8-(furan-3-yl)-1,1,5a,7a,11b-pentamethyl-5b,6,7,7a,8,11b,13,13a-octahydrooxireno[4,4a]isochromeno[6,5-g][2]benzoxepine-3,10,12(1H,5aH,10aH)-trione |
| Obacune |
| Oxireno[4',5']pyrano[4',3':5,6]naphth[2,1-c]oxepin-3,10,12(1H,5aH,10aH)-trione, 8-(3-furanyl)-5b,6,7,7a,8,11b,13,13a-octahydro-1,1,5a,7a,11b-pentamethyl-, (5aR,5bR,7aS,8S,10aS,11aR,11bR,13aR)- |
| CasiMirolide |
