CAS 53-59-8|Nicotinamide adenine dinucleotide phosphate

Introduction：Basic information about CAS 53-59-8|Nicotinamide adenine dinucleotide phosphate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. BiologicalActivity
3. Chemical & Physical Properties
4. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
5. Safety Information
6. Customs
7. Synonyms

Common Name	Nicotinamide adenine dinucleotide phosphate
CAS Number	53-59-8	Molecular Weight	744.41
Density	/	Boiling Point	/
Molecular Formula	C₂₁H₂₉N₇O₁₇P₃	Melting Point	/
MSDS	/	Flash Point	/

Names

Name	NADP zwitterion
Synonym	More Synonyms

BiologicalActivity

Description	NADP is nicotinamide adenine dinucleotide phosphate, acting as a key cofactor for electron transfer in the metabolism of all organisms, being alternately oxidized (NADP+) and reduced (NADPH).
Related Catalog	Natural Products >>OthersResearch Areas >>Others
Target	Human Endogenous Metabolite
References	[1]. Zhao FL, et al. A genetically encoded biosensor for in vitro and in vivo detection of NADP+. Biosens Bioelectron. 2016 Mar 15;77:901-6.

Chemical & Physical Properties

Molecular Formula	C₂₁H₂₉N₇O₁₇P₃
Molecular Weight	744.41
PSA	397.05000
LogP	-7.30
InChIKey	ZKJOXOJMGXFSPF-QYZPTAICSA-N
SMILES	NC(=O)c1ccc[n+](C2OC(COP(=O)([O-])OP(=O)(O)OCC3OC(n4cnc5c(N)ncnc54)C(OP(=O)(O)O)C3O)C(O)C2O)c1.O
Storage condition	−20°C
Water Solubility	H2O: 50 mg/mL, clear, slightly yellow

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UU3440000

CHEMICAL NAME :: Pyridinium, 3-carbamoyl-1-beta-D-ribofuranosyl-, hydroxide, 5',5'-ester with adenosine 2'- (dihydrogen phosphate) 5'-(trihydrogen pyrophosphate), inner salt

CAS REGISTRY NUMBER :: 53-59-8

BEILSTEIN REFERENCE NO. :: 3885115

LAST UPDATED :: 199709

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C21-H28-N7-O17-P3

MOLECULAR WEIGHT :: 743.47

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 3166 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 20,160,1986 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - A1187 No. of Facilities: 58 (estimated) No. of Industries: 2 No. of Occupations: 2 No. of Employees: 332 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - A1187 No. of Facilities: 327 (estimated) No. of Industries: 1 No. of Occupations: 4 No. of Employees: 4926 (estimated) No. of Female Employees: 3928 (estimated)

Safety Information

Hazard Codes	Xi:Irritant;
Risk Phrases	R36/37/38
Safety Phrases	S26-S36
WGK Germany	3
RTECS	UU3440000
HS Code	2924199090

Customs

HS Code	2924199090
Summary	2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Synonyms

NADPH

NADP-ox

NADP+

COENZYME II

b-Nicotinamide Adenine Dinucleotide Phosphate

cozymaseii

β-Nicotinamide Adenine Dinucleotide Phosphate

TPNH

b-NADP

β-Triphosphopyridine Nucleotide

TPN

Triphosphopyridinnucleotid

3-Carbamoyl-1-b-D-ribofuranosylpyridinium Hydroxide 5'®5'-Ester with Adenosine 2'-(Dihydrogen Phosphate) 5'-(Trihydrogen Pyrophosphate) Inner Salt

Co II

Adenosine 5'-(Trihydrogen Diphosphate) 2'-(Dihydrogen Phosphate) P'®5'-Ester with 3-(Aminocarbonyl)-1-b-D-ribofuranosylpyridinium Hydroxide Inner Salt

Beta-NADP,Monopotassium Salt

MFCD10567218

NADP

b-TPN

β-Nicotinamide adenine dinucleotide phosphate (NADP)

Triphosphopyridine Nucleotid

Triphosphopyridine nucleotide

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