CAS 2019-42-3|DEQUALINIUM IODIDE

Introduction：Basic information about CAS 2019-42-3|DEQUALINIUM IODIDE, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Chemical & Physical Properties
3. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
4. Safety Information
5. Articles27
6. Synonyms

Common Name	DEQUALINIUM IODIDE
CAS Number	2019-42-3	Molecular Weight	710.47400
Density	/	Boiling Point	/
Molecular Formula	C₃₀H₄₀I₂N₄	Melting Point	>300ºC (dec.)(lit.)
MSDS	ChineseUSA	Flash Point	/
Symbol	GHS07	Signal Word	Warning

Names

Name	1-[10-(4-amino-2-methylquinolin-1-ium-1-yl)decyl]-2-methylquinolin-1-ium-4-amine,diiodide
Synonym	More Synonyms

Chemical & Physical Properties

Melting Point	>300ºC (dec.)(lit.)
Molecular Formula	C₃₀H₄₀I₂N₄
Molecular Weight	710.47400
Exact Mass	710.13400
PSA	59.80000
LogP	1.34060
InChIKey	BTXPITUAZUILEM-UHFFFAOYSA-N
SMILES	Cc1cc(N)c2ccccc2[n+]1CCCCCCCCCC[n+]1c(C)cc(N)c2ccccc21.[I-].[I-]

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: VA0705000

CHEMICAL NAME :: Quinaldinium, 1,1'-decamethylenebis(4-amino-, diiodide

CAS REGISTRY NUMBER :: 2019-42-3

LAST UPDATED :: 199603

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C30-H40-N4.2I

MOLECULAR WEIGHT :: 710.54

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 21 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPPMAB Journal of Pharmacy and Pharmacology. (Pharmaceutical Soc. of Great Britain, 1 Lambeth High St., London SEI 7JN, UK) V.1- 1949- Volume(issue)/page/year: 8,110,1956

Safety Information

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi: Irritant;
Risk Phrases	36/37/38
Safety Phrases	26-36
RIDADR	NONH for all modes of transport
RTECS	VA0705000

Articles27

Antimicrobial topical agents used in the vagina.

Curr. Probl. Dermatol. 40 , 36-47, (2011)

Vaginally applied antimicrobial agents are widely used in the vagina in women with lower genital tract infections. An 'antimicrobial' is a general term that refers to a group of drugs that are effecti...

Dequalinium induces cytotoxicity in human leukemia NB4 cells by downregulation of Raf/MEK/ERK and PI3K/Akt signaling pathways and potentiation of specific inhibitors of these pathways.

Leuk. Res. 38(7) , 795-803, (2014)

Delocalized lipophilic cation dequalinium (DQA) selectively accumulates in mitochondria and displays anticancer activity in different malignancies. Our previous studies indicate a DQA-induced cytotoxi...

N-palmitoyl-ethanolamine (PEA) induces peripheral antinociceptive effect by ATP-sensitive K+-channel activation.

J. Pharmacol. Sci. 118(2) , 156-60, (2012)

Although the antinociceptive effects of N-palmitoyl-ethanolamine (PEA) were first characterized nearly 50 years ago, the identity of the mechanism that mediates these actions has not been elucidated. ...

Synonyms

1,1'-(Decane-1,10-diyl)bis(4-amino-2-methylquinolinium) diiodide

Quinaldinium,1,1'-decamethylenebis(4-amino-,diiodide

Dequalinium iodide

Dequalinium Diiodide

1,1'-Decamethylenebis(4-aminoquinaldinium iodide)

EINECS 217-964-5

Quinolinium,1,1'-(1,10-decanediyl)bis(4-amino-2-methyl-,diiodide

MFCD00191973

Recommended......