CAS 1185-53-1|Trometamol hydrochloride

Introduction:Basic information about CAS 1185-53-1|Trometamol hydrochloride, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameTrometamol hydrochloride
CAS Number1185-53-1Molecular Weight157.596
Density1.05 g/mL at 20 °CBoiling Point357ºC at 760 mmHg
Molecular FormulaC4H12ClNO3Melting Point150-152 °C
MSDSUSAFlash Point169.7ºC

Names

Name2-Amino-2-(hydroxymethyl)-1,3-propanediol hydrochloride
SynonymMore Synonyms

Trometamol hydrochloride BiologicalActivity

DescriptionTrometamol hydrochloride (Tromethamine hydrochloride) is a biologically inert amino alcohol of low toxicity, which buffers carbon dioxide and acids in vitro and in vivo. Trometamol hydrochloride is an effective amine compound for pH control in the physiological range[1].
Related CatalogSignaling Pathways >>Others >>OthersResearch Areas >>Metabolic Disease
References

[1]. Nahas GG, et al. Guidelines for the treatment of acidaemia with THAM. Drugs. 1998 Feb;55(2):191-224.

Chemical & Physical Properties

Density1.05 g/mL at 20 °C
Boiling Point357ºC at 760 mmHg
Melting Point150-152 °C
Molecular FormulaC4H12ClNO3
Molecular Weight157.596
Flash Point169.7ºC
Exact Mass157.050568
PSA86.71000
InChIKeyQKNYBSVHEMOAJP-UHFFFAOYSA-N
SMILESCl.NC(CO)(CO)CO
Storage conditionStore at RT.
StabilityStable. Incompatible with strong oxidizing agents, bases, moisture.
Water SolubilitySOLUBLE

Safety Information

Personal Protective Equipmentdust mask type N95 (US);Eyeshields;Gloves
Hazard CodesXi:Irritant
Risk PhrasesR36/37/38
Safety PhrasesS26-S36
RIDADRNONH for all modes of transport
WGK Germany3
RTECSTY2900000
HS Code2922199090

Customs

HS Code2922199090
Summary2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

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Synonyms

Tris(hydroxymethyl)aminomethane Hydrochloride
2-Amino-2-(hydroxymethyl)-1,3-propanediol hydrochloride
MFCD00012590
2-Amino-2-(hydroxymethyl)propan-1,3-diolhydrochlorid
2-Amino-2-(hydroxymethyl)propane-1,3-diol hydrochloride (1:1)
TRIS HCl
2-amino-2-(hydroxymethyl)propane-1,3-diol,hydrochloride
1,3-Propanediol, 2-amino-2-(hydroxymethyl)-, hydrochloride (1:1)
tromethamine hydrochloride
Tris(hydroxymethyl)aminomethane hydrochloride(TRIS-HCl)
2-Amino-2-(hydroxymethyl)-1,3-propanediol hydrochloride (1:1)
Tris(hydroxymethyl)aminomethane HCl
Tris(hydroxymethyl)aminometha
1,3-Propanediol, 2-amino-2-(hydroxymethyl)-, hydrochloride
TRIS HCl,TRIS hydrochloride,Tris(hydroxymethyl)aminomethane hydrochloride
Tris Hydrochloride
EINECS 214-684-5
Trimethylolaminomethane Hydrochloride
2-Amino-2-(hydroxymethyl)propane-1,3-diol hydrochloride
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