Introduction：Basic information about CAS 14636-12-5|Terlipressin acetate salt, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Terlipressin acetate salt |
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| CAS Number | 14636-12-5 | Molecular Weight | 1227.372 |
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| Density | 1.5±0.1 g/cm3 | Boiling Point | 1824.0±65.0 °C at 760 mmHg |
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| Molecular Formula | C52H74N16O15S2 | Melting Point | / |
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| MSDS | / | Flash Point | 1056.9±34.3 °C |
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Names
| Name | Terlipressin |
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| Synonym | More Synonyms |
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Terlipressin acetate salt BiologicalActivity
| Description | Terlipressin is a potent vasoconstrictor that acts via V1 receptors on arteriolar smooth muscle cells. Terlipressin can result in splanchnic vasoconstriction augmenting systemic arterial blood pressure with beneficial circulatory and renal effects that would be expected to also ameliorate the key pathophysiological changes responsible for the development of refractory ascites |
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| Related Catalog | Signaling Pathways >>GPCR/G Protein >>Vasopressin ReceptorResearch Areas >>Cardiovascular DiseasePeptides |
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| References | [1]. Jao YT et al. Refractory torsade de pointes induced by terlipressin (Glypressin). Int J Cardiol, 2016 Jul 30, 222:135-140. |
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Chemical & Physical Properties
| Density | 1.5±0.1 g/cm3 |
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| Boiling Point | 1824.0±65.0 °C at 760 mmHg |
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| Molecular Formula | C52H74N16O15S2 |
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| Molecular Weight | 1227.372 |
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| Flash Point | 1056.9±34.3 °C |
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| Exact Mass | 1226.496094 |
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| PSA | 563.45000 |
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| LogP | -6.75 |
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| Vapour Pressure | 0.0±0.3 mmHg at 25°C |
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| Index of Refraction | 1.664 |
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| InChIKey | BENFXAYNYRLAIU-QSVFAHTRSA-N |
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| SMILES | NCCCCC(NC(=O)C1CCCN1C(=O)C1CSSCC(NC(=O)CNC(=O)CNC(=O)CN)C(=O)NC(Cc2ccc(O)cc2)C(=O)NC(Cc2ccccc2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(N)=O)C(=O)N1)C(=O)NCC(N)=O |
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| Storage condition | -20°C |
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Synonyms
| (2S)-1-{[(4R,7S,10S,13S,16S,19R)-19-{[({[(Aminoacetyl)amino]acetyl}amino)acetyl]amino}-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-benzyl-16-(4-hydroxybenzyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl}-N-{(2S)-6-amino-1-[(2-amino-2-oxoethyl)amino]-1-oxohexan-2-yl}pyrrolidine-2-carboxamide (non-preferred name) |
| Terlipressin |
| EINECS 238-680-8 |
| MFCD00155450 |
| (2S)-1-{[(4R,7S,10S,13S,16S,19R)-19-{[({[(Aminoacetyl)amino]acetyl}amino)acetyl]amino}-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-benzyl-16-(4-hydroxybenzyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl}-N-{(2S)-6-amino-1-[(2-amino-2-oxoethyl)amino]-1-oxo-2-hexanyl}-2-pyrrolidinecarboxamide |
| N-(N-(N-Glycylglycyl)glycyl)-8-L-lysinevasopressin |
| Terlipressin Acetate |
