CAS 26544-34-3|Apiin
| Common Name | Apiin | ||
|---|---|---|---|
| CAS Number | 26544-34-3 | Molecular Weight | 564.492 |
| Density | 1.7±0.1 g/cm3 | Boiling Point | 942.2±65.0 °C at 760 mmHg |
| Molecular Formula | C26H28O14 | Melting Point | 230ºC (dec.) |
| MSDS | ChineseUSA | Flash Point | 316.7±27.8 °C |
Names
| Name | Apiin |
|---|---|
| Synonym | More Synonyms |
Apiin BiologicalActivity
| Description | Apiin, a major constituent of Apium graveolens leaves with anti-inflammatory properties. Apiin shows significant inhibitory activity on nitrite (NO) production (IC50 = 0.08 mg/mL) in-vitro and iNOS expression (IC50 = 0.049 mg/ mL) in LPS-activated J774.A1 cells[1]. |
|---|---|
| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Inflammation/Immunology |
| References | [1]. Mencherini T, et al. An extract of Apium graveolens var. dulce leaves: structure of the major constituent, apiin, and its anti-inflammatory properties. J Pharm Pharmacol. 2007 Jun;59(6):891-7. |
Chemical & Physical Properties
| Density | 1.7±0.1 g/cm3 |
|---|---|
| Boiling Point | 942.2±65.0 °C at 760 mmHg |
| Melting Point | 230ºC (dec.) |
| Molecular Formula | C26H28O14 |
| Molecular Weight | 564.492 |
| Flash Point | 316.7±27.8 °C |
| Exact Mass | 564.147888 |
| PSA | 228.97000 |
| LogP | 0.74 |
| Vapour Pressure | 0.0±0.3 mmHg at 25°C |
| Index of Refraction | 1.744 |
| InChIKey | NTDLXWMIWOECHG-YRCFQSNFSA-N |
| SMILES | O=c1cc(-c2ccc(O)cc2)oc2cc(OC3OC(CO)C(O)C(O)C3OC3OCC(O)(CO)C3O)cc(O)c12 |
| Storage condition | 2-8C |
Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| RIDADR | NONH for all modes of transport |
| WGK Germany | 1 |
| HS Code | 29389090 |
Articles7
More Articles| Evaluation of detection sensitivity in comprehensive two-dimensional liquid chromatography separations of an active pharmaceutical ingredient and its degradants. Anal. Bioanal. Chem 407(1) , 265-77, (2015) In this paper, we describe the findings of a study aimed at assessing the detection sensitivity of comprehensive two-dimensional high-performance liquid chromatography (LCxLC) separation of a degraded... | |
| Bioavailability of apigenin from apiin-rich parsley in humans. Ann. Nutr. Metab. 50(3) , 167-72, (2006) Absorption and excretion of apigenin after the ingestion of apiin-rich food, i.e. parsley, was tested.Eleven healthy subjects (5 women, 6 men) in the age range of 23-41 years and with an average body ... | |
| [Studies on the chemical constituents of the aerial parts of Seseli mairei]. Zhong Yao Cai 30(1) , 42-4, (2007) To study the chemical constituents of the aerial parts of Seseli mairei Wolf.The chemical constituents have been separated with manifold chromatography methods, and their structures were determined hy... |
Synonyms
| APIIN |
| Apioside |
| APIGENIN-7-APIOGLUCOSIDE |
| 5-Hydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-7-yl 4-O-[(3R,4R)-3,4-dihydroxy-4-(hydroxymethyl)tetrahydrofuran-2-yl]-β-D-glucopyranoside |
| apigenin-7-O-apiosyl(1->2)glucoside |
| apigenin 7-O-apiosylglucoside |
| 4',5,7-Trihydroxyflavone-7-apiosylglucoside |
| 4H-1-Benzopyran-4-one, 5-hydroxy-2-(4-hydroxyphenyl)-7-[[4-O-[(3R,4R)-tetrahydro-3,4-dihydroxy-4-(hydroxymethyl)-2-furanyl]-β-D-glucopyranosyl]oxy]- |
| 5-Hydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-7-yl 4-O-[(3R,4R)-3,4-dihydroxy-4-(hydroxymethyl)tetrahydro-2-furanyl]-β-D-glucopyranoside |
| 7-(2-APIOSYLGLUCOSYL)APIGENIN |
| Apigenin-7-(2-O-apiosylglucoside) |
| 7-[(2-O-D-Apio-b-D-furanosyl-b-D-glucopyranosyl)oxy]-5-hydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one |
| Apigenin-7-apiosylglucoside |
| EINECS 247-780-0 |
