CAS 123-77-3|Azodicarbonamide
Introduction：Basic information about CAS 123-77-3|Azodicarbonamide, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Azodicarbonamide | ||
|---|---|---|---|
| CAS Number | 123-77-3 | Molecular Weight | 116.079 |
| Density | 1.9±0.1 g/cm3 | Boiling Point | 241.3±23.0 °C at 760 mmHg |
| Molecular Formula | C2H4N4O2 | Melting Point | 220-225 °C (dec.)(lit.) |
| MSDS | ChineseUSA | Flash Point | 99.7±22.6 °C |
| Symbol | GHS08 | Signal Word | Danger |
Names
| Name | Azodicarbonamide |
|---|---|
| Synonym | More Synonyms |
Chemical & Physical Properties
| Density | 1.9±0.1 g/cm3 |
|---|---|
| Boiling Point | 241.3±23.0 °C at 760 mmHg |
| Melting Point | 220-225 °C (dec.)(lit.) |
| Molecular Formula | C2H4N4O2 |
| Molecular Weight | 116.079 |
| Flash Point | 99.7±22.6 °C |
| Exact Mass | 116.033424 |
| PSA | 110.90000 |
| LogP | -0.85 |
| Vapour Pressure | 0.0±1.1 mmHg at 25°C |
| Index of Refraction | 1.680 |
| InChIKey | XOZUGNYVDXMRKW-AATRIKPKSA-N |
| SMILES | NC(=O)N=NC(N)=O |
| Stability | Highly flammable. Incompatible with strong oxidizing agents, strong acids, strong bases, heavy metal salts. |
| Water Solubility | SOLUBLE IN HOT WATER |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >6400 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 440 mg/kg
- TOXIC EFFECTS :
- Lungs, Thorax, or Respiration - respiratory stimulation Gastrointestinal - hypermotility, diarrhea Skin and Appendages - hair
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 42 gm/kg/10D-C
- TOXIC EFFECTS :
- Endocrine - evidence of thyroid hypofunction Endocrine - changes in thyroid weight
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 233 gm/kg/4W-C
- TOXIC EFFECTS :
- Endocrine - evidence of thyroid hypofunction
- TYPE OF TEST :
- TCLo - Lowest published toxic concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 207 mg/m3/6H/2W-I
- TOXIC EFFECTS :
- Liver - changes in liver weight Nutritional and Gross Metabolic - weight loss or decreased weight gain
- TYPE OF TEST :
- TCLo - Lowest published toxic concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 204 mg/m3/6H/13W-I
- TOXIC EFFECTS :
- Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol)
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 252 mg/kg/1W-I
- TOXIC EFFECTS :
- Kidney, Ureter, Bladder - hematuria Related to Chronic Data - death
- TYPE OF TEST :
- TCLo - Lowest published toxic concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 217 mg/m3/6H/2W-I
- TOXIC EFFECTS :
- Liver - changes in liver weight Nutritional and Gross Metabolic - weight loss or decreased weight gain
- TYPE OF TEST :
- TCLo - Lowest published toxic concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 204 mg/m3/6H/13W-I
- TOXIC EFFECTS :
- Liver - changes in liver weight Nutritional and Gross Metabolic - weight loss or decreased weight gain
MUTATION DATA - TYPE OF TEST :
- Mutation in microorganisms
- TEST SYSTEM :
- Bacteria - Salmonella typhimurium
- DOSE/DURATION :
- 100 ug/plate
- REFERENCE :
- ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 8(Suppl 7),1,1986 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 81713 No. of Facilities: 1753 (estimated) No. of Industries: 32 No. of Occupations: 60 No. of Employees: 43147 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 81713 No. of Facilities: 1210 (estimated) No. of Industries: 18 No. of Occupations: 29 No. of Employees: 42296 (estimated) No. of Female Employees: 17091 (estimated)
- TYPE OF TEST :
- Mutation in microorganisms
- TEST SYSTEM :
- Bacteria - Salmonella typhimurium
- DOSE/DURATION :
- 100 ug/plate
- REFERENCE :
- ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 8(Suppl 7),1,1986 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 81713 No. of Facilities: 1753 (estimated) No. of Industries: 32 No. of Occupations: 60 No. of Employees: 43147 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 81713 No. of Facilities: 1210 (estimated) No. of Industries: 18 No. of Occupations: 29 No. of Employees: 42296 (estimated) No. of Female Employees: 17091 (estimated)
Safety Information
| Symbol | GHS08 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H334 |
| Supplemental HS | Risk of explosion if heated under confinement. |
| Precautionary Statements | P261-P284-P304 + P340-P342 + P311 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Faceshields;Gloves |
| Hazard Codes | Xn:Harmful |
| Risk Phrases | R42;R44 |
| Safety Phrases | S22-S24-S37 |
| RIDADR | UN 3242 4.1/PG 2 |
| WGK Germany | 1 |
| RTECS | LQ1040000 |
| Packaging Group | II |
| Hazard Class | 4.1 |
| HS Code | 2924199090 |
Customs
| HS Code | 2927000090 |
|---|---|
| Summary | 2927000090 other diazo-, azo- or azoxy-compounds。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0% |
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| Assessment of the determination of azodicarbonamide and its decomposition product semicarbazide: investigation of variation in flour and flour products. J. Agric. Food Chem. 59(17) , 9313-8, (2011) Azodicarbonamide, as a bleaching agent and improving agent, is a permitted food additive in certain countries and can be determined by high-performance liquid chromatography. However, it partially deg... | |
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Synonyms
| Carbamoyliminourea |
| Diazene-1,2-dicarboxamide |
| (E)-carbamoyliminourea |
| MFCD00007958 |
| EINECS 204-650-8 |
