CAS 55954-61-5|Pseudohypericin
| Common Name | Pseudohypericin | ||
|---|---|---|---|
| CAS Number | 55954-61-5 | Molecular Weight | 520.443 |
| Density | 2.0±0.1 g/cm3 | Boiling Point | 994.7±65.0 °C at 760 mmHg |
| Molecular Formula | C30H16O9 | Melting Point | / |
| MSDS | ChineseUSA | Flash Point | 569.2±30.8 °C |
| Symbol | GHS07 | Signal Word | Warning |
Names
| Name | pseudohypericin |
|---|---|
| Synonym | More Synonyms |
Pseudohypericin BiologicalActivity
| Description | Pseudohypericin and its congener Hypericin are the major hydroxylated phenanthroperylenediones present in Hypericum species. Pseudohypericin shows anti-HIV activity[1][2]. |
|---|---|
| Related Catalog | Signaling Pathways >>Anti-infection >>HIVResearch Areas >>Infection |
| In Vitro | Pseudohypericin shows antiretroviral activity[1]. |
| References | [1]. Lavie G, et al. Studies of the mechanisms of action of the antiretroviral agents hypericin and pseudohypericin. Proc Natl Acad Sci U S A. 1989 Aug;86(15):5963-7. [2]. Zheng X, et al. Apoptosis of THP-1 Macrophages Induced by Pseudohypericin-Mediated Sonodynamic Therapy Through the Mitochondria-Caspase Pathway. Cell Physiol Biochem. 2016;38(2):545-57. |
Chemical & Physical Properties
| Density | 2.0±0.1 g/cm3 |
|---|---|
| Boiling Point | 994.7±65.0 °C at 760 mmHg |
| Molecular Formula | C30H16O9 |
| Molecular Weight | 520.443 |
| Flash Point | 569.2±30.8 °C |
| Exact Mass | 520.079407 |
| PSA | 175.75000 |
| LogP | 6.75 |
| Vapour Pressure | 0.0±0.3 mmHg at 25°C |
| Index of Refraction | 2.169 |
| InChIKey | NODGUBIGZKATOM-UHFFFAOYSA-N |
| SMILES | Cc1cc(=O)c2c(O)c3c(O)cc(O)c4c5c(O)cc(O)c6c(O)c7c(=O)cc(CO)c8c1c2c(c34)c(c65)c78 |
| Storage condition | 2-8°C |
Safety Information
| Symbol | GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302 |
| Precautionary Statements | P301 + P312 + P330 |
| Hazard Codes | Xi |
| Risk Phrases | 22 |
| Safety Phrases | 22-36 |
| RIDADR | NONH for all modes of transport |
Articles26
More Articles| Hypericum perforatum: pharmacokinetic, mechanism of action, tolerability, and clinical drug-drug interactions. Phytother Res. 28(5) , 643-55, (2014) Hypericum perforatum (HP) belongs to the Hypericaceae family and is one of the oldest used and most extensively investigated medicinal herbs. The medicinal form comprises the leaves and flowering tops... | |
| The main components of St John's Wort inhibit low-density lipoprotein atherogenic modification: a beneficial "side effect" of an OTC antidepressant drug? Free Radic. Res. 41(2) , 234-41, (2007) Hypericin and pseudohypericin are polycyclic-phenolic structurally related compounds found in Hypericum perforatum L. (St John's wort). As hypericin has been found to bind to LDL one may assume that i... | |
| Rapid and efficient purification of naphthodianthrones from St. John's wort extract by using liquid-liquid extraction and SEC. J. Sep. Sci. 32(9) , 1374-82, (2009) Hypericin and pseudohypericin, the main naphthodianthrones present in Hypericum species are among the most promising natural products, but the research concerning their biological activities is hinder... |
Synonyms
| Phenanthro(1,10,9,8-opgra)perylene-7,14-dione,1,3,4,6,8,13-hexahydroxy-10-(hydroxymethyl)-11-methyl-,stereoisomer |
| 1,3,4,6,8,13-hexahydroxy-10-hydroxymethyl-11-methyl-phenanthro[1,10,9,8-opqra]perylene-7,14-dione |
| Psuedohypericin |
| 1,3,4,6,8,13-Hexahydroxy-10-hydroxymethyl-11-methyl-phenanthro[1,10,9,8-opqra]perylen-7,14-dion |
| C30H16O9 |
| 1,3,4,6,8,13-Hexahydroxy-10-(hydroxymethyl)-11-methylphenanthro[1,10,9,8-opqra]perylene-7,14-dione |
| Phenanthro[1,10,9,8-opqra]perylene-7,14-dione, 1,3,4,6,8,13-hexahydroxy-10-(hydroxymethyl)-11-methyl- |
| BIDD:PXR0086 |
| MFCD00133794 |
