CAS 5417-84-5|9H-Purine,6-(ethylthio)-
Introduction：Basic information about CAS 5417-84-5|9H-Purine,6-(ethylthio)-, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 9H-Purine,6-(ethylthio)- | ||
|---|---|---|---|
| CAS Number | 5417-84-5 | Molecular Weight | 180.23000 |
| Density | 1.39g/cm3 | Boiling Point | 460.2ºC at 760mmHg |
| Molecular Formula | C7H8N4S | Melting Point | / |
| MSDS | ChineseUSA | Flash Point | 232.1ºC |
| Symbol | GHS08 | Signal Word | Warning |
Names
| Name | 6-ethylsulfanyl-7H-purine |
|---|---|
| Synonym | More Synonyms |
Chemical & Physical Properties
| Density | 1.39g/cm3 |
|---|---|
| Boiling Point | 460.2ºC at 760mmHg |
| Molecular Formula | C7H8N4S |
| Molecular Weight | 180.23000 |
| Flash Point | 232.1ºC |
| Exact Mass | 180.04700 |
| PSA | 79.76000 |
| LogP | 1.46490 |
| Index of Refraction | 1.758 |
| InChIKey | XTJLAIOQORFEOI-UHFFFAOYSA-N |
| SMILES | CCSc1ncnc2nc[nH]c12 |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Parenteral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 164 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JPMSAE Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961- Volume(issue)/page/year: 71,618,1982
Safety Information
| Symbol | GHS08 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H351 |
| Precautionary Statements | P281 |
| Personal Protective Equipment | Eyeshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges |
| Hazard Codes | Xn |
| Risk Phrases | 40 |
| Safety Phrases | 22-36 |
| RIDADR | UN 2811 6.1/PG 3 |
| RTECS | UO8535000 |
| HS Code | 2933990090 |
Customs
| HS Code | 2933990090 |
|---|---|
| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
Articles3
More Articles| Induction of the c-ski proto-oncogene by phorbol ester correlates with induction of megakaryocyte differentiation. Oncogene 9(5) , 1407-16, (1994) Overexpression of v-ski blocks the terminal differentiation of chicken erythroblasts, and in cooperation with v-sea causes transformation of these cells, indicating that c-ski may play a role in regul... | |
| 6-ethylmercaptopurine-mediated growth inhibition of HL-60 cells in vitro irrespective of purine salvage. Cancer Chemother. Pharmacol. 25(3) , 189-94, (1989) A variety of purine analogs inhibit the growth and induce the differentiation of human promyelocytic leukemia (HL-60) cells that lack the purine salvage enzyme hypoxanthine-guanine phosphoribosyltrans... | |
| Differential effect of 6-ethylmercaptopurine on c-myc expression in wild-type and HGPRT-deficient HL-60 cells. Cancer Chemother. Pharmacol. 27(3) , 171-7, (1990) A variety of compounds inhibit the growth and induce differentiation of human promyelocytic leukemia (HL-60) cells. HL-60 subclones that lack the purine salvage enzyme hypoxanthine-guanine phosphoribo... |
Synonyms
| 6-Ethylmercaptopurine |
| QA 69 |
| 6-ETHYLTHIOPURINE |
| 6-Ethyl MP |
