CAS 382146-66-9|Bacopaside II

Introduction:Basic information about CAS 382146-66-9|Bacopaside II, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameBacopaside II
CAS Number382146-66-9Molecular Weight929.09600
Density1.43Boiling Point/
Molecular FormulaC47H76O18Melting Point/
MSDSChineseUSAFlash Point/

Names

Namebacopaside ii(p)
SynonymMore Synonyms

Bacopaside II BiologicalActivity

DescriptionBacopaside II, an extract from the medicinal herb Bacopa monnieri, blocks the Aquaporin-1 (AQP1) water channel and impairs migration of cells that express AQP1. Bacopaside II induces cell cycle arrest and apoptosis[1][2].
Related CatalogSignaling Pathways >>Apoptosis >>ApoptosisResearch Areas >>Cancer
References

[1]. Palethorpe HM, et al. The Aquaporin 1 Inhibitor Bacopaside II Reduces Endothelial Cell Migration and Tubulogenesis and Induces Apoptosis. Int J Mol Sci. 2018 Feb 26;19(3). pii: E653.

[2]. Smith E, et al. The Purified Extract from the Medicinal Plant Bacopa monnieri, Bacopaside II, Inhibits Growth of Colon Cancer Cells In Vitro by Inducing Cell Cycle Arrest and Apoptosis. Cells. 2018 Jul 21;7(7). pii: E81.

Chemical & Physical Properties

Density1.43
Molecular FormulaC47H76O18
Molecular Weight929.09600
Exact Mass928.50300
PSA276.14000
InChIKeyWZWPYJOPCULCLQ-UOXCDNDQSA-N
SMILESCC(C)=CC1COC23CC4(CO2)C(CCC2C5(C)CCC(OC6OC(CO)C(O)C(OC7OC(CO)C(O)C(O)C7O)C6OC6OC(CO)C(O)C6O)C(C)(C)C5CCC24C)C3C1(C)O
Storage condition2-8°C

Safety Information

RIDADRNONH for all modes of transport

Synonyms

BACOPASIDE II(SH)
Bacopaside II
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