CAS 121-60-8|4-Acetamidobenzenesulfonyl chloride

Introduction：Basic information about CAS 121-60-8|4-Acetamidobenzenesulfonyl chloride, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Chemical & Physical Properties
3. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
4. Safety Information
5. Customs
6. Articles2
7. Synonyms

Common Name	4-Acetamidobenzenesulfonyl chloride
CAS Number	121-60-8	Molecular Weight	233.672
Density	1.5±0.1 g/cm3	Boiling Point	426.8±28.0 °C at 760 mmHg
Molecular Formula	C₈H₈ClNO₃S	Melting Point	142-145 °C (dec.)(lit.)
MSDS	ChineseUSA	Flash Point	211.9±24.0 °C
Symbol	GHS05, GHS07	Signal Word	Danger

Names

Name	N-Acetylsulfanilyl chloride
Synonym	More Synonyms

Chemical & Physical Properties

Density	1.5±0.1 g/cm3
Boiling Point	426.8±28.0 °C at 760 mmHg
Melting Point	142-145 °C (dec.)(lit.)
Molecular Formula	C₈H₈ClNO₃S
Molecular Weight	233.672
Flash Point	211.9±24.0 °C
Exact Mass	232.991348
PSA	71.62000
LogP	1.55
Vapour Pressure	0.0±1.0 mmHg at 25°C
Index of Refraction	1.586
InChIKey	GRDXCFKBQWDAJH-UHFFFAOYSA-N
SMILES	CC(=O)Nc1ccc(S(=O)(=O)Cl)cc1
Water Solubility	SLIGHTLY SOLUBLE

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DB8837500

CHEMICAL NAME :: Benzenesulfonyl chloride, 4-(acetylamino)-

CAS REGISTRY NUMBER :: 121-60-8

LAST UPDATED :: 199710

DATA ITEMS CITED :: 7

MOLECULAR FORMULA :: C8-H8-Cl-N-O3-S

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >3200 mg/kg

TOXIC EFFECTS :: Behavioral - muscle weakness Behavioral - ataxia

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0533583

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 25 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Behavioral - muscle weakness Behavioral - ataxia

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0533583

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1600 mg/kg

TOXIC EFFECTS :: Behavioral - muscle weakness Behavioral - ataxia

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0533583

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 50 mg/kg

TOXIC EFFECTS :: Behavioral - muscle weakness Behavioral - ataxia

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0533583

Safety Information

Symbol	GHS05, GHS07
Signal Word	Danger
Hazard Statements	H314-H335
Precautionary Statements	P261-P280-P305 + P351 + P338-P310
Personal Protective Equipment	Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
Hazard Codes	C:Corrosive
Risk Phrases	R34
Safety Phrases	S26-S36/37/39-S45-S28B
RIDADR	UN 3261 8/PG 2
WGK Germany	3
RTECS	DB8837500
Packaging Group	II
Hazard Class	8
HS Code	29242995

Customs

HS Code	2924299090
Summary	2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles2

High-performance liquid chromatographic determination of tramadol and its O-desmethylated metabolite in blood plasma. Application to a bioequivalence study in humans.

J. Chromatogr. A. 949(1-2) , 11-22, (2002)

Simultaneous HPLC determination of the analgetic agent tramadol, its major pharmacodynamically active metabolite (O-desmethyltramadol) in human plasma is described. Simple methods for the preparation ...

Synthesis of hapten and production of a monoclonal antibody against a derivative of L-hydroxyproline, a special amino acid in hydrolyzed animal protein.

J. Environ. Sci. Health B 48(1) , 9-15, (2013)

China's government has prohibited the addition of simply hydrolyzed animal protein from solid leather waste into milk. The objective of this study was to produce a monoclonal antibody against L-hydrox...

Synonyms

4-Acetamidobenzenesulfonyl Chloride

Sulfanilyl chloride, N-acetyl-

P-ACETAMIDOBENZENE SULFONYL CHLORIDE ASC

4-ACETAMIDOBENZENESULFONYLCHLORIDE

P-ACETYLSULPHANILYL CHLORIDE

ASC

UNII-LIX4M9AIVM

p-Acetamidophenylsulfonyl chloride

4-ACETAMINOBENZENESULFONYL CHLORIDE

N-Acetylsulfanilylchloride

p-Acetylaminobenzenesulfonyl chloride

EINECS 204-485-1

4-Acetamidophenylsulfonyl chloride

N-Acetylsulfanilyl chloride

N-Acetylsulfanyl Chloride

p-Acetaminobenzenesulfonyl chloride

4-(ACETYLAMINO)BENZENESULFONYL CHLORIDE

p-Acetamidobenzenesulfonyl chloride

4-Chlorosulfonylacetanilide

4-ACETAMIDOBENZENESULPHONYL CHLORIDE/N-ACETYLSULPHANILYL CHLORIDE] 121-60-8

N-ACETYLSULPHANILYL CHLORIDE

4-ACETAMIDEBENZENESULFONYL CHLORIDE

Acetanilide-p-sulfonyl chloride

4-ACETAMIDOBENZENE SULFONYL CHLORIDE

N-Acetyl sulfanilyl chloride

p-(Chlorosulfonyl)acetanilide

4-ACETAMIDOBENZENESULFONYL CHLORIDE FOR SYNTHESIS

4-ACETAMIDOBENZENESULPHONYL CHLORIDE

4-Acetamidobenzene-1-Sulfonyl Chloride

MFCD00007442

Benzenesulfonyl chloride, 4-(acetylamino)-

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