CAS 70667-26-4|ornoprostil

Introduction：Basic information about CAS 70667-26-4|ornoprostil, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. ornoprostil BiologicalActivity
3. Chemical & Physical Properties
4. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
5. Synonyms

Common Name	ornoprostil
CAS Number	70667-26-4	Molecular Weight	410.54
Density	1.112g/cm3	Boiling Point	549.8ºC at 760 mmHg
Molecular Formula	C₂₃H₃₈O₆	Melting Point	/
MSDS	/	Flash Point	178.8ºC

Names

Name	methyl 7-[(1R,2R,3R)-3-hydroxy-2-[(E,3S,5S)-3-hydroxy-5-methylnon-1-enyl]-5-oxocyclopentyl]-6-oxoheptanoate
Synonym	More Synonyms

ornoprostil BiologicalActivity

Description	Ornoprostil is a prostaglandin E1 analogue. Ornoprostil is orally active and can be used for gastric ulcer research[1].
Related Catalog	Signaling Pathways >>Others >>OthersResearch Areas >>Inflammation/Immunology
References	[1]. Matsuhashi N, et al. Multiple strictures of the small intestine after long-term nonsteroidal anti-inflammatory drug therapy. Am J Gastroenterol. 1992 Sep;87(9):1183-6.

Chemical & Physical Properties

Density	1.112g/cm3
Boiling Point	549.8ºC at 760 mmHg
Molecular Formula	C₂₃H₃₈O₆
Molecular Weight	410.54
Flash Point	178.8ºC
Exact Mass	410.26700
PSA	100.90000
LogP	3.37860
Index of Refraction	1.526
InChIKey	BBRBUTFBTUFFBU-LHACABTQSA-N
SMILES	CCCCC(C)CC(O)C=CC1C(O)CC(=O)C1CC(=O)CCCCC(=O)OC

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UK8370000

CHEMICAL NAME :: Prost-13-en-1-oic acid, 11,15-dihydroxy-17,20-dimethyl-6,9-dioxo-, methyl ester, (11-alpha,13E)-

CAS REGISTRY NUMBER :: 70667-26-4

LAST UPDATED :: 199612

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C23-H38-O6

MOLECULAR WEIGHT :: 410.61

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 44 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: -,249,1990

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 4900 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: -,249,1990

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 10200 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: -,249,1990

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 35 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: -,249,1990

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 43500 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: -,249,1990

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 30 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: -,249,1990

Synonyms

Ornoprostilum [Latin]

6-Oxo-17(S),20-dimethyl-PGE(1)-methylester

(17S)-17,20-dimethyl-6-oxo-PGE1 methyl ester

Ornoprostilo [Spanish]

ornoprostil

Ornoprostilum

Ornoprostilo

Ronoprost

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