Introduction：Basic information about CAS 127-21-9|1,3-dichlorotetrafluoroacetone, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 1,3-dichlorotetrafluoroacetone |
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| CAS Number | 127-21-9 | Molecular Weight | 198.93100 |
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| Density | 1.52 | Boiling Point | 44 °C |
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| Molecular Formula | C3Cl2F4O | Melting Point | / |
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| MSDS | / | Flash Point | None |
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Names
| Name | 1,3-dichloro-1,1,3,3-tetrafluoropropan-2-one |
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| Synonym | More Synonyms |
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Chemical & Physical Properties
| Density | 1.52 |
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| Boiling Point | 44 °C |
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| Molecular Formula | C3Cl2F4O |
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| Molecular Weight | 198.93100 |
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| Flash Point | None |
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| Exact Mass | 197.92600 |
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| PSA | 17.07000 |
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| LogP | 2.21870 |
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| Index of Refraction | 1.33 |
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| InChIKey | QRKKTXWUDLJYCV-UHFFFAOYSA-N |
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| SMILES | O=C(C(F)(F)Cl)C(F)(F)Cl |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- UC1575000
- CHEMICAL NAME :
- 2-Propanone, 1,3-dichloro-1,1,3,3-tetrafluoro-
- CAS REGISTRY NUMBER :
- 127-21-9
- BEILSTEIN REFERENCE NO. :
- 0509313
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 7
- MOLECULAR FORMULA :
- C3-Cl2-F4-O
- MOLECULAR WEIGHT :
- 198.93
- WISWESSER LINE NOTATION :
- GXFFVXGFF
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 61 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Gastrointestinal - ulceration or bleeding from stomach
- REFERENCE :
- TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 7,592,1965
- TYPE OF TEST :
- LC50 - Lethal concentration, 50 percent kill
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 4800 mg/m3
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold Behavioral - excitement
- REFERENCE :
- TLSMA6 Trudy Leningradskogo Sanitarno-Gigienicheskogo Meditsinskogo Instituta. (Leningrad, Russia) V.1-145, 1949-82. Discontinued. Volume(issue)/page/year: 111,15,1975
- TYPE OF TEST :
- LC50 - Lethal concentration, 50 percent kill
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 4500 mg/m3
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold Behavioral - excitement
- REFERENCE :
- TLSMA6 Trudy Leningradskogo Sanitarno-Gigienicheskogo Meditsinskogo Instituta. (Leningrad, Russia) V.1-145, 1949-82. Discontinued. Volume(issue)/page/year: 111,15,1975
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 180 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#01749
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 91 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Skin and Appendages - primary irritation (after topical exposure)
- REFERENCE :
- TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 7,592,1965 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-RUSSIA:STEL 2 mg/m3;Skin JAN 1993
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Safety Information
| Hazard Codes | T |
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| Risk Phrases | R23/24/25:Toxic by inhalation, in contact with skin and if swallowed . R34:Causes burns. R36/37/38:Irritating to eyes, respiratory system and skin . R24/25:Toxic in contact with skin and if swallowed . |
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| Safety Phrases | S26-S36/37/39-S45-S23 |
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| RIDADR | 2927 |
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| RTECS | UC1575000 |
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| Packaging Group | III |
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| Hazard Class | 6.1(b) |
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| HS Code | 2914700090 |
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Customs
| HS Code | 2914700090 |
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| Summary | HS: 2914700090 halogenated, sulphonated, nitrated or nitrosated derivatives of ketones and quinones, whether or not with other oxygen function Tax rebate rate:9.0% Supervision conditions:none VAT:17.0% MFN tariff:5.5% General tariff:30.0% |
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Synonyms
| sym-Dichlorotetrafluoroacetone |
| 1,3-Dichloro-1,1,3,3-tetrafluoroacetone |
| MFCD00000776 |
| symm. Dichlorotetrafluoroacetone |
| 1,3-Dichlorotetrafluoroacetone |
| 1,3-Dichloro-1,1,3,3-tetrafluoro-2-propanone |
| Stauffer N-3,412 |
| DCTFA |
| 1,3-Dichlor-1,1,3,3-tetrafluor-aceton |
| Dichlorotetrafluoroacetone |
| sym.-Tetrafluorodichloroacetone |
| 1,3-dichlorotetrafluoropropan-2-one |
| 2-PROPANONE,1,3-DICHLORO-1,1,3,3-TETRAFLUORO |
| EINECS 204-829-0 |
