Introduction：Basic information about CAS 83546-42-3|2'-Fluoro-5-ethylarabinosyluracil, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 2'-Fluoro-5-ethylarabinosyluracil |
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| CAS Number | 83546-42-3 | Molecular Weight | 274.25 |
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| Density | 1.6±0.1 g/cm3 | Boiling Point | / |
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| Molecular Formula | C11H15FN2O5 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | 5-ethyl-1-[(2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione |
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| Synonym | More Synonyms |
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2'-Fluoro-5-ethylarabinosyluracil BiologicalActivity
| Description | 1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-5-ethyl-2,4(1H,3H)-pyrimidinedione is a thymidine analogue. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis[1]. |
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| Related Catalog | Signaling Pathways >>Cell Cycle/DNA Damage >>Nucleoside Antimetabolite/AnalogResearch Areas >>Others |
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| References | [1]. Cavanagh BL, et al. Thymidine analogues for tracking DNA synthesis. Molecules. 2011 Sep 15;16(9):7980-93. |
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Chemical & Physical Properties
| Density | 1.6±0.1 g/cm3 |
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| Molecular Formula | C11H15FN2O5 |
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| Molecular Weight | 274.25 |
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| Exact Mass | 290.091400 |
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| PSA | 124.78000 |
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| LogP | -0.88 |
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| Index of Refraction | 1.587 |
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| InChIKey | SWFJAJRDLUUIOA-IBCQBUCCSA-N |
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| SMILES | CCc1cn(C2OC(CO)C(O)C2F)c(=O)[nH]c1=O |
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Synonyms
| 1-[5-(2-Fluoroethyl)-D-arabinopyranosyl]-2,4(1H,3H)-pyrimidinedione |
| FEAU |
| 1-Dfafeu |
| 1-(2-Deoxy-2-fluoroarabinofuranosyl)-5-ethyluracil |
| 1-[(3S,4R,5S)-6-(2-Fluoroethyl)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl]-2,4(1H,3H)-pyrimidinedione |
| 2,4(1H,3H)-Pyrimidinedione, 1-[(5ξ)-6,7-dideoxy-7-fluoro-D-arabino-heptopyranosyl]- |
| 1-[(5ξ)-6,7-Dideoxy-7-fluoro-D-arabino-heptopyranosyl]-2,4(1H,3H)-pyrimidinedione |
| 2'-Fluoro-5-ethylarabinosyluracil |
| 1-[(5ξ)-6,7-Dideoxy-7-fluoro-D-arabino-heptopyranosyl]pyrimidine-2,4(1H,3H)-dione |
