CAS 35109-88-7|2-Iodoadenosine

Introduction:Basic information about CAS 35109-88-7|2-Iodoadenosine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Name2-Iodoadenosine
CAS Number35109-88-7Molecular Weight393.14
Density2.7±0.1 g/cm3Boiling Point776.3±70.0 °C at 760 mmHg
Molecular FormulaC10H12IN5O4Melting Point200ºC (dec.)
MSDS/Flash Point423.3±35.7 °C

Names

Name(2R,3R,4S,5R)-2-(6-amino-2-iodopurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol
SynonymMore Synonyms

2-Iodoadenosine BiologicalActivity

Description2-Iodoadenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].
Related CatalogResearch Areas >>CancerSignaling Pathways >>Cell Cycle/DNA Damage >>Nucleoside Antimetabolite/Analog
References

[1]. Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500.  

Chemical & Physical Properties

Density2.7±0.1 g/cm3
Boiling Point776.3±70.0 °C at 760 mmHg
Melting Point200ºC (dec.)
Molecular FormulaC10H12IN5O4
Molecular Weight393.14
Flash Point423.3±35.7 °C
Exact Mass392.993378
PSA139.54000
LogP-1.04
Vapour Pressure0.0±2.8 mmHg at 25°C
Index of Refraction1.994
InChIKeyMGEBVSZZNFOIRB-UUOKFMHZSA-N
SMILESNc1nc(I)nc2c1ncn2C1OC(CO)C(O)C1O
Storage conditionRefrigerator, Under Inert Atmosphere

Safety Information

Hazard CodesXi: Irritant;
Risk PhrasesR36/37/38
Safety Phrases26

Synonyms

2-iodo-2',3'-O-isopropylidene-adenosine
Adenosine,2-iodo
MFCD01320413
2-idodadenosine
6-Amino-2-iodo-9-(β-D-ribofuranosyl)purine
2-Iodoadenosine
2-Iodo-D-adenosine
Adenosine, 2-iodo-
2-IODO ADENOSINE
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