Introduction:Basic information about CAS 35109-88-7|2-Iodoadenosine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 2-Iodoadenosine |
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| CAS Number | 35109-88-7 | Molecular Weight | 393.14 |
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| Density | 2.7±0.1 g/cm3 | Boiling Point | 776.3±70.0 °C at 760 mmHg |
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| Molecular Formula | C10H12IN5O4 | Melting Point | 200ºC (dec.) |
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| MSDS | / | Flash Point | 423.3±35.7 °C |
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Names
| Name | (2R,3R,4S,5R)-2-(6-amino-2-iodopurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol |
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| Synonym | More Synonyms |
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2-Iodoadenosine BiologicalActivity
| Description | 2-Iodoadenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>Cell Cycle/DNA Damage >>Nucleoside Antimetabolite/Analog |
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| References | [1]. Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500. |
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Chemical & Physical Properties
| Density | 2.7±0.1 g/cm3 |
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| Boiling Point | 776.3±70.0 °C at 760 mmHg |
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| Melting Point | 200ºC (dec.) |
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| Molecular Formula | C10H12IN5O4 |
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| Molecular Weight | 393.14 |
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| Flash Point | 423.3±35.7 °C |
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| Exact Mass | 392.993378 |
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| PSA | 139.54000 |
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| LogP | -1.04 |
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| Vapour Pressure | 0.0±2.8 mmHg at 25°C |
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| Index of Refraction | 1.994 |
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| InChIKey | MGEBVSZZNFOIRB-UUOKFMHZSA-N |
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| SMILES | Nc1nc(I)nc2c1ncn2C1OC(CO)C(O)C1O |
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| Storage condition | Refrigerator, Under Inert Atmosphere |
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Safety Information
| Hazard Codes | Xi: Irritant; |
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| Risk Phrases | R36/37/38 |
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| Safety Phrases | 26 |
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Synonyms
| 2-iodo-2',3'-O-isopropylidene-adenosine |
| Adenosine,2-iodo |
| MFCD01320413 |
| 2-idodadenosine |
| 6-Amino-2-iodo-9-(β-D-ribofuranosyl)purine |
| 2-Iodoadenosine |
| 2-Iodo-D-adenosine |
| Adenosine, 2-iodo- |
| 2-IODO ADENOSINE |